39205
Dimethylaminomethyl-polystyrene
200-400 mesh particle size, extent of labeling: 3-4 mmol/g base loading, matrix crosslinked with 2% DVB
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Synonym(s):
Benzyldimethylamine polymer-bound, Copolymer of styrene and divinylbenzene, dimethylaminomethylated, Polystyrene crosslinked with divinylbenzene, dimethylaminomethylated
Linear Formula:
CH2N(CH3)2 - [CH2CH(C6H55)]n
Recommended Products
reaction suitability
reaction type: solution phase peptide synthesis
reactivity: proton reactive
extent of labeling
3-4 mmol/g base loading
impurities
≤0.5 mmol/g Cl- (resin)
matrix
crosslinked with 2% DVB
particle size
200-400 mesh
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General description
Dimethylaminomethyl-polystyrene, also known as benzyldimethylamine, is a polystyrene-supported resin crosslinked with divinylbenzene that is commonly used in solution phase peptide synthesis.
Application
Dimethylaminomethyl-polystyrene is used as a resin to synthesize hydrophobic dipeptides such as bis-phenylalanines that can be used in the study of peptide and protein aggregation. Additionally, it can also be utilized for neutralizing acidic solution in a reaction mixture due to its proton reactive nature.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Synthesis of bis-Phenylalanine, A Novel Eight-Membered Cyclic Dipeptide
BV Falcone
Synthetic Communications, 38, 411-418 (2008)
Synthesis and properties of new nucleotide analogues possessing squaramide moieties as new phosphate isosters
K Seio
European Journal of Organic Chemistry (2005)
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