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Merck
CN

390593

1-(1-Adamantyl)ethylamine hydrochloride

99%

Synonym(s):

α-Methyltricyclo[3.3.1.13,7]-decane-1-methanamine hydrochloride, Rimantadine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H21N · HCl
CAS Number:
1501-84-4
Molecular Weight:
215.76
NACRES:
NA.22
PubChem Substance ID:
24864331
UNSPSC Code:
12352100
MDL number:
MFCD00072023
Assay:
99%

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InChI

1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H/t8?,9-,10+,11-,12-;

SMILES string

Cl.C[C@H](N)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI key

OZBDFBJXRJWNAV-MZHJCFSPSA-N

assay

99%

mp

>300 °C (lit.)

functional group

amine

Quality Level

100

Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN3379
MKCM6621
MKCL0481
MKCD9884
MKCC5148

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G G U Rohde
Der Internist, 52(9), 1047-1052 (2011-08-03)
Influenza infections have important socio-economic consequences. Risk groups identified so far include small children and elderly adults with comorbidities. In recent years in addition to seasonal influenza an outbreak of avian influenza occurred in 2005 and the new H1N1 pandemic
V G Belolipetskaia et al.
Eksperimental'naia i klinicheskaia farmakologiia, 74(7), 38-40 (2011-09-08)
Comparative pharmacokinetics of anti-influenza drug composition Antigrippin-maximum administered in capsules and a powder for preparing solutions has been studied after single administraton in a group of 18 healthy volunteers. Both preparations [manufactured by the Antiviral Research and Production Corporation (St
V S Smirnov et al.
Voprosy virusologii, 57(3), 23-27 (2012-08-22)
The purpose of the study was to evaluate the modulating effect of glutamyl-tryptophan (EW), glycyrrhizic acid (GA), and their combination on the course of experimental infection caused by influenza A (H3N2) virus in mice. The animals were infected with influenza
George Atiee et al.
Journal of clinical pharmacology, 52(9), 1410-1419 (2011-10-01)
Peramivir, an intravenously administered neuraminidase inhibitor, may be used concomitantly with other influenza antivirals. Two studies were conducted to assess the potential for pharmacokinetic interactions of peramivir when coadministered with oseltamivir or rimantadine. Twenty-one healthy subjects were enrolled in each
Georgina Cirrincione-Dall et al.
Journal of clinical pharmacology, 52(8), 1255-1264 (2011-11-01)
Preclinical data suggest increased antiviral activity and less viral resistance when neuraminidase inhibitors and adamantanes are used in combination to harness the complementary effects of their different mechanisms of action. Healthy volunteers were randomized to 5-day oral treatment with oseltamivir
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