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Sigma-Aldrich

D-Glucose-13C6

≥99 atom % 13C, ≥99% (CP)

Synonym(s):

Labeled Glucose, D-Glucose-ul-13C, Dextrose-13C6

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About This Item

Empirical Formula (Hill Notation):
13C6H12O6
CAS Number:
110187-42-3
Molecular Weight:
186.11
MDL number:
MFCD00037544
UNSPSC Code:
12142200
PubChem Substance ID:
24864278
NACRES:
NA.12

isotopic purity

≥99 atom % 13C

Quality Level

200

Assay

≥99% (CP)

form

powder

optical activity

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

technique(s)

bio NMR: suitable
protein expression: suitable
protein purification: suitable

mp

150-152 °C (lit.)

mass shift

M+6

SMILES string

O[13CH2][13C@H]1O[13C@H](O)[13C@H](O)[13C@@H](O)[13C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1

InChI key

WQZGKKKJIJFFOK-NYKRWLDMSA-N

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Application

D-Glucose-13C6 has been used:
  • for de novo fatty acid (FA) synthesis
  • as a component in tracing media for the analysis of stable isotope tracer
  • in minimal media for recombinant protein production
  • for cell suspension

Biochem/physiol Actions

D-Glucose-13C6 functions as a tracer and helps to access glucose kinetics in vivo.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Frank Malz et al.
Carbohydrate research, 342(1), 65-70 (2006-12-06)
Double Quantum (DQ) NMR, which utilizes the magnetic dipole interaction between the (13)C atoms, was used for the complete assignment of the (13)C NMR resonances to the corresponding carbon ring positions for the monoclinic and triclinic allomorphs of methyl 4'-O-methyl-beta-D-cellobioside-(13)C(12)(1-(13)C(12))
Proceedings: Teratogenic actions of C13-glucose on the early development of the mouse embryo.
H Spielman et al.
Naunyn-Schmiedeberg's archives of pharmacology, 287 Suppl, R86-R86 (1975-01-01)
RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma
Houles T, et al.
Cancer Research, canres-ca2215 (2018)
Zoran Dinev et al.
Carbohydrate research, 341(10), 1743-1747 (2006-04-11)
A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-1-phosphate and UMP-morpholidate. The uridine diphospho(13C6)glucose was used in the structural identification of (1-->3)-beta-D-glucan from Lolium multiflorum.
Metabolic profiling reveals a coordinated response of isolated lamb's (Valerianella locusta, L.) lettuce cells to sugar starvation and low oxygen stress
Victor BMM, et al.
Postharvest biology and technology, 126, 23-33 (2017)
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