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Sigma-Aldrich

Dimethylamine solution

2.0 M in methanol

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Synonym(s):
N,N-Dimethylamine
Linear Formula:
(CH3)2NH
CAS Number:
124-40-3
Molecular Weight:
45.08
Beilstein:
605257
MDL number:
MFCD00008288
UNSPSC Code:
12352116
PubChem Substance ID:
24864215
NACRES:
NA.22

form

liquid

Quality Level

200

concentration

1.90 -2.20 M (NaOH, titration)
2.0 M in methanol

density

0.775 g/mL at 25 °C

SMILES string

CNC

InChI

1S/C2H7N/c1-3-2/h3H,1-2H3

InChI key

ROSDSFDQCJNGOL-UHFFFAOYSA-N

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General description

Dimethylamine, a secondary amine, is used as a raw material for the production of many agrichemicals and pharmaceuticals. The solvents dimethylformamide (DMF) and dimethylacetamide (DMA) are derived from dimethylamine. It is also used as a precursor for the preparation of amido derivatives.

Application

Dimethylamine can be used as a precursor for the preparation of a number of chemical building blocks such as dimethyl(3-chloropropyl)amine , 2-chloro-N,N-dimethylethanimidamide , and 4, 6-dichloro-2-(dimethylamino)-1,3,5-triazine .

Packaging

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

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Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3

Target Organs

Eyes, Respiratory system

WGK

WGK 2

Flash Point(F)

41.0 °F

Flash Point(C)

5 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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4-Dimethylaminobutyraldehyde diethyl acetal
FENG R-l, et al.
JOURNAL-SHANDONG UNIVERSITY OF SCIENCE AND TECHNOLOGY NATURAL SCIENCE, 5 (2011)
Synthesis of 2-amino-4-imino-4, 5-dihydrothiazoles from N-sulfonyl-α -chloroamidines and thiourea
Abdelaal SM and Bauer L
Journal of Heterocyclic Chemistry, 25(6), 1849-1856 (1988)
Synthesis of 3-{4-[4-dimethylamino-6-(4-methyl-2-oxo-2H-chromen-7-yloxy)-[1, 3, 5] triazin-2-ylamino]-phenyl}-2-phenyl-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-thiazolidin-4-one and their biological evaluation
Patel D, et al.
Medicinal Chemistry Research, 21(10), 2926-2944 (2012)
Methylamines
van Gysel A B and Musin W
Ullmann's Encyclopedia of Industrial Chemistry (1997)
C Mulder et al.
Journal of neural transmission (Vienna, Austria : 1996), 109(9), 1203-1208 (2002-08-31)
Nitric oxide (NO) may play a role in the pathophysiology of Alzheimer's disease (AD). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, is involved in regulation of NO production. Recently it has been reported that dimethylarginine dimethylaminohydrolase, an enzyme
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