37870
3-(2,4-Dihydroxyphenyl)propionic acid
≥95.0% (HPLC)
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Synonym(s):
2,4-Dihydroxyhydrocinnamic acid, Hydroumbellic acid
Empirical Formula (Hill Notation):
C9H10O4
CAS Number:
Molecular Weight:
182.17
Beilstein:
2694769
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
≥95.0% (HPLC)
form
solid
mp
158-162 °C
SMILES string
OC(=O)CCc1ccc(O)cc1O
InChI
1S/C9H10O4/c10-7-3-1-6(8(11)5-7)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
InChI key
HMCMTJPPXSGYJY-UHFFFAOYSA-N
Related Categories
General description
3-(2,4-Dihydroxyphenyl)propionic acid is a 3,4-dihydroxyphenylalanine (DOPA) analog. It is a building block for heterocyclic compounds.
Application
3-(2,4-Dihydroxyphenyl)propionic acid (DHPPA) may be used as substrate for the o-diphenolase in microplate assays of serum and hemocyte supernatants from QXR3 and wild type oysters for the quantitation of o-diphenolase activity.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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B Morin et al.
The Biochemical journal, 330 ( Pt 3), 1059-1067 (1998-05-23)
A major product of hydroxy-radical addition to tyrosine is 3, 4-dihydroxyphenylalanine (DOPA) which has reducing properties. Protein-bound DOPA (PB-DOPA) has been shown to be a major component of the stable reducing species formed during protein oxidation under several conditions. The
Kathryn Newton et al.
Developmental and comparative immunology, 28(6), 565-569 (2004-06-05)
QX is a fatal disease in Sydney rock oysters (Saccostrea glomerata) that results from infection by the protistan parasite, Marteilia sydneyi. Since 1997, the New South Wales Fisheries Service has bred S. glomerata for resistance to QX disease. The current
A new synthesis of psoralene [(author's transl)].
O Dann et al.
Archiv der Pharmazie, 308(2), 121-130 (1975-02-01)
Violetta Mohos et al.
Biomolecules, 10(3) (2020-03-12)
Flavonoids are abundant polyphenols in nature. They are extensively biotransformed in enterocytes and hepatocytes, where conjugated (methyl, sulfate, and glucuronide) metabolites are formed. However, bacterial microflora in the human intestines also metabolize flavonoids, resulting in the production of smaller phenolic
Eszter Fliszár-Nyúl et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 131, 110732-110732 (2020-09-18)
Polyphenolic compounds (including flavonoids, chalcones, phenolic acids, and furanocoumarins) represent a common part of our diet, but are also the active ingredients of several dietary supplements and/or medications. These compounds undergo extensive metabolism by human biotransformation enzymes and the microbial
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