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Merck
CN

376205

Triphenylsilylamine

97%

Synonym(s):

Aminotriphenylsilane, TPSA, Triphenylaminosilane

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About This Item

Linear Formula:
(C6H5)3SiNH2
CAS Number:
Molecular Weight:
275.42
EC Number:
224-147-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
2941367
MDL number:
Assay:
97%
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InChI key

GLQOALGKMKUSBF-UHFFFAOYSA-N

InChI

1S/C18H17NSi/c19-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H,19H2

SMILES string

N[Si](c1ccccc1)(c2ccccc2)c3ccccc3

assay

97%

mp

60-62 °C (lit.)

storage temp.

2-8°C

General description

Triphenylsilylamine is a silyl compound.

Application

Triphenylsilylamine may be used in the following studies:
  • Preparation of dimers of the type [Ti(μ-NR)(NMe2)2]2 (R = 1-adamantyl, (t)Bu, SiPh3).
  • Silylation during the pretreatment of fused silica capillary surface to achieve a homogeneous film.
  • Preparation of triphenylsilylsulfinylamine, via reaction with thionylchloride.
  • To investigate the molecular tuning effect of silanation treatment for HZSM-5 crystals.
  • Synthesis of 9-aminopyrido[3′,3′:4,5]pyrrolo[1,2-c]pyrimidine (9-aminosubstituted derivative).

signalword

Warning

pictograms

Exclamation mark

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Cătălin Buiu et al.
Current computer-aided drug design, 10(3), 237-249 (2014-01-01)
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Meng-Yao Wang et al.
Journal of agricultural and food chemistry, 67(7), 1823-1830 (2019-01-25)
The increasing prevalence of fungal diseases, continual development of resistance, and stringent environmental regulations have revealed an urgent need to develop more selective, safer, resistance-breaking, and cost-effective fungicides. However, most new fungicidal lead compounds fail in their late stages of
Bernhard X Mayer-Helm et al.
Journal of separation science, 27(4), 335-342 (2004-09-01)
Two highly phenylated tetramethyl-p-silphenylene-diphenylsiloxane copolymers were coated on fused silica capillary columns and used as stationary phases in GC. The copolymers offered new insights into the coating process and column preparation due to their physicochemical properties. The fused silica capillary
Manish Sud
Journal of chemical information and modeling, 56(12), 2292-2297 (2016-12-28)
MayaChemTools is a growing collection of Perl scripts, modules, and classes to support a variety of computational drug discovery needs, such as manipulation and analysis of data, generation of two-dimensional (2D) fingerprints, similarity searching, and calculation of physicochemical properties. MayaChemTools
Gilles H Goetz et al.
Molecular pharmaceutics, 14(2), 386-393 (2016-12-31)
EPSA is an experimental descriptor of molecular polarity obtained from chromatographic retention in supercritical fluid chromatography (SFC) systems, previously shown by Goetz et al. to correlate with passive permeability of cyclic peptides. The present study focuses on EPSA in relation

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