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Safety Information

369063

Sigma-Aldrich

2-Bromo-4-chloro-6-fluoroaniline

98%

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About This Item

Linear Formula:
BrC6H2(Cl)(F)NH2
CAS Number:
Molecular Weight:
224.46
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

mp

41-43 °C (lit.)

functional group

bromo
chloro
fluoro

SMILES string

Nc1c(F)cc(Cl)cc1Br

InChI

1S/C6H4BrClFN/c7-4-1-3(8)2-5(9)6(4)10/h1-2H,10H2

InChI key

HBHBARSMRVAINH-UHFFFAOYSA-N

General description

2-Bromo-4-chloro-6-fluoroaniline is an aniline derivative.

Application

2-Bromo-4-chloro-6-fluoroaniline may be used in the preparation of fragment A of an orally bioavailable and CNS penetrant bradykinin1antagonist.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Process development of a potent bradykinin 1 antagonist.
Menzel K, et al.
Organic Process Research & Development, 13(3), 519-524 (2009)

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