Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

368342

Sigma-Aldrich

Azide exchange resin, azide on Amberlite IRA-400

16-50 mesh

Sign Into View Organizational & Contract Pricing


About This Item

MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22

form

beads

reaction suitability

reaction type: solution phase peptide synthesis

particle size

16-50 mesh

capacity

3.8 mmol/g

Looking for similar products? Visit Product Comparison Guide

Application

Azide exchange resin, azide on Amberlite IRA-400 is a resin commonly used to replace activated and nonactivated alkyl halides with azide functional group. It has been used in the synthesis of natural products (±)-oxomaritidine and nornicotine.
It can also be used to prepare:
  • Different imidazolium derived ionic liquid azides.
  • An azide synthon 1-(azidomethyl)-4-[18F]-fluorobenzene, which is used to label an amino acid and a neuropeptide using click chemistry.

Legal Information

Amberlite is a trademark of DuPont de Nemours, Inc.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lars C Moeller et al.
Thyroid : official journal of the American Thyroid Association, 19(6), 639-644 (2009-05-19)
Knowledge on the action of thyroid hormone (TH) is augmented by the study of tissue responses to TH in vitro. In order to support the growth of cells in vitro, calf serum (CS) is usually added to the medium to
Hassner, A; Stern, M.
Angewandte Chemie (International Edition in English), 25, 478-478 (1986)
Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers
Baxendale IR, et al.
Journal of the Chemical Society. Perkin Transactions 1, 143-154 (2002)
New strategy for the preparation of clickable peptides and labeling with 1-(azidomethyl)-4-[18F]-fluorobenzene for PET
Thonon D, et al.
Bioconjugate Chemistry, 20(4), 817-823 (2009)
Liquid azide salts and their reactions with common oxidizers IRFNA and N2O4
Schneider S, et al.
Inorganic Chemistry, 47(13), 6082-6089 (2008)

Articles

Since the preparation of the first organic azide, phenyl azide, by Peter Griess in 1864 this energy-rich and versatile class of compounds has enjoyed considerable interest.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service