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Sigma-Aldrich

Didodecylamine

≥97.0% (GC)

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Synonym(s):
Di-n-dodecylamine, Dilaurylamine, N,N-Didodecylamine, N-Dodecyl-1-dodecanamine
Linear Formula:
[CH3(CH2)11]2NH
CAS Number:
Molecular Weight:
353.67
Beilstein:
1777050
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

≥97.0% (GC)

form

powder

mp

45-49 °C

SMILES string

CCCCCCCCCCCCNCCCCCCCCCCCC

InChI

1S/C24H51N/c1-3-5-7-9-11-13-15-17-19-21-23-25-24-22-20-18-16-14-12-10-8-6-4-2/h25H,3-24H2,1-2H3

InChI key

MJCJUDJQDGGKOX-UHFFFAOYSA-N

Related Categories

General description

Didodecylamine is a secondary amine. It is reported as standard amine enhancer and its dermal enhancement properties has been studied using in vitro diffusion cell techniques. Solidification point of dodecylamine has been reported to be 26.2°C.

Application

Didodecylamine may be used:
  • to promote the crystal growth of 2D nanosheets of GdOCl with approximately square cross sections
  • to investigate the effect of alkyl chain length of amine on phase transfer of aqueous synthesized gold nanoparticles (AuNPs) from water to toluene
  • in the preparation of novel class of liquid crystalline complexes, by the interaction of copper nitrate

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Note on the preparation of n-dodecylamine and di-n-dodecylamine from n-dodecyl chloride by means of anhydrous liquid ammonia.
Wibaut JP, et al.
Rec. Trav. Chim., 57(4), 456-458 (1938)
Novel Thermotropic Mesophases of Copper Complexes with Long-Chain Aliphatic Amines.
Paleos CM, et al.
Mol. Cryst. Liq. Cryst., 161(1), 373-383 (1988)
In vitro evaluation of a series of Azone analogs as dermal penetration enhancers: IV. Amines.
Michniak BB, et al.
International Journal of Pharmaceutics, 116(2), 201-209 (1995)
Kenneth R Kort et al.
Small (Weinheim an der Bergstrasse, Germany), 11(3), 329-334 (2014-08-28)
While much progress has been achieved in the shape-controlled synthesis of nanocrystals, chemical strategies to define morphology remain primarily empirical. Here, a mechanistic study of the influence of different coordinating ligands on the kinetics and thermodynamics of crystal growth during
Katarzyna Soliwoda et al.
Langmuir : the ACS journal of surfaces and colloids, 30(23), 6684-6693 (2014-06-04)
In the present paper we describe a phase transfer of aqueous synthesized gold nanoparticles (AuNPs) from water to toluene using secondary amines: dioctylamine, didodecylamine, and dioctadecylamine. The effect of the hydrocarbon chain length and amount of amines on the transfer

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