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Merck
CN

36295

2,3-Dichloro-1-propanol

≥97.0% (GC)

Synonym(s):

Glycerol-α,β-dichlorohydrin

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About This Item

Linear Formula:
ClCH2CHClCH2OH
CAS Number:
Molecular Weight:
128.99
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-470-0
Beilstein/REAXYS Number:
1732060
MDL number:
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Product Name

2,3-Dichloro-1-propanol, ≥97.0% (GC)

InChI key

ZXCYIJGIGSDJQQ-UHFFFAOYSA-N

InChI

1S/C3H6Cl2O/c4-1-3(5)2-6/h3,6H,1-2H2

SMILES string

OCC(Cl)CCl

assay

≥97.0% (GC)

density

1.360 g/mL at 20 °C (lit.)

functional group

chloro
hydroxyl

Quality Level

Application

2,3-Dichloro-1-propanol may be employed as carbon and energy supplement for the growth of Pseudomonas putida strain (MC4).

General description

2,3-Dichloro-1-propanol belongs to the group of chloropropanols. Inhibitory effects of 2,3-dichloro-1-propanol on T cell both in vivo and in vitro is reported. Improved enantioselective resolution of (R,S)-2,3-dichloro-1-propanol to (S)-2, 3-dichloro-1-propanol by whole cells of a recombinant Escherichia coli in n-heptane-aqueous biphasic system is reported.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

199.4 °F

flash_point_c

93 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Jing Lu et al.
International immunopharmacology, 17(2), 321-328 (2013-07-16)
2,3-Dichloro-1-propanol (2,3-DCP) is a member of a group of chemicals known as chloropropanols. Currently, immunotoxicity of 2,3-DCP has not been reported. In the present study, we studied its inhibitory effects on T cell both in vivo and in vitro. The
A J Effendi et al.
Applied and environmental microbiology, 66(7), 2882-2887 (2000-07-06)
2,3-Dichloro-1-propanol is more chemically stable than its isomer, 1, 3-dichloro-2-propanol, and is therefore more difficult to degrade. The isolation of bacteria capable of complete mineralization of 2, 3-dichloro-1-propanol was successful only from enrichments at high pH. The bacteria thus isolated
C Aguilar et al.
Journal of chromatography. A, 867(1-2), 207-218 (2000-02-12)
On-line combination of equilibrium sorptive enrichment and gas chromatography is used for the analysis of a group of pollutants varying widely in polarity and volatility in aqueous samples at trace levels. For the ESE process open-tubular traps were used. The
K Fujishiro et al.
Fukuoka igaku zasshi = Hukuoka acta medica, 85(8), 247-250 (1994-08-01)
The toxicity of dichloropropanols (DCPs) was investigated by hematological and blood chemical examination. Solutions of two isomers of DCPs, 1,3-dichloro-2-propanol (DC2P) and 2,3-dichloro-1-propanol (DC1P) were dissolved in saline at a concentration of 100 mg/ml and 0.1 ml of each was
Muhammad Irfan Arif et al.
Applied and environmental microbiology, 78(17), 6128-6136 (2012-07-04)
A Pseudomonas putida strain (MC4) that can utilize 2,3-dichloro-1-propanol (DCP) and several aliphatic haloacids and haloalcohols as sole carbon and energy source for growth was isolated from contaminated soil. Degradation of DCP was found to start with oxidation and concomitant

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