Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

349852

Sigma-Aldrich

[3-(Ethoxycarbonyl)propyl]triphenylphosphonium bromide

97%

Synonym(s):

NSC 269919

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C2H5O2C(CH2)3P(C6H5)3Br
CAS Number:
50479-11-3
Molecular Weight:
457.34
MDL number:
MFCD00274610
UNSPSC Code:
12352108
PubChem Substance ID:
24861713
NACRES:
NA.22

Quality Level

100

Assay

97%

reaction suitability

reaction type: C-C Bond Formation

mp

165-167 °C (lit.)

SMILES string

[Br-].CCOC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C24H26O2P.BrH/c1-2-26-24(25)19-12-20-27(21-13-6-3-7-14-21,22-15-8-4-9-16-22)23-17-10-5-11-18-23;/h3-11,13-18H,2,12,19-20H2,1H3;1H/q+1;/p-1

InChI key

JPZMNVPVVYVXAD-UHFFFAOYSA-M

Related Categories

Application

Reactant for:
  • Asymmetric synthesis of antihypercholesterolemic ezetimibe via Wittig reaction
  • Wittig reactions
[3-(Ethoxycarbonyl)propyl]triphenylphosphonium bromide can be used:
  • As a reactant in the synthesis of spirocyclic GPR119 agonists.
  • In the synthesis of cyclic acetal intermediate of azadirachtin, a terpenoid found in the neem tree Azadirachta indica.
  • To prepare a catechin metabolite named 5-(3,4,5-trihydroxyphenyl)valeric acid.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Inhibitory activity of catechin metabolites produced by intestinal microbiota on proliferation of HeLa cells
Hara-Terawaki A, et al.
Biological & Pharmaceutical Bulletin, 40(8), 1331-1335 (2017)
Synthetic studies of azadirachtin. Synthesis of the cyclic acetal intermediate in the naturally occurring form
Nishikimi Y, et al.
The Journal of Organic Chemistry, 54(14), 3354-3359 (1989)
Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure
Harada K, et al.
Bioorganic & medicinal chemistry letters, 28(7), 1228-1233 (2018)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service