Skip to Content
Merck
CN
All Photos(2)

Key Documents

View All Documentation

333328

Sigma-Aldrich

6-Ethoxy-2-benzothiazolesulfonamide

97%

Synonym(s):

6-Ethoxyzolamide, Ethoxzolamide

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C9H10N2O3S2
CAS Number:
452-35-7
Molecular Weight:
258.32
EC Number:
207-199-5
MDL number:
MFCD00057089
UNSPSC Code:
12352100
PubChem Substance ID:
24860121
NACRES:
NA.22

Assay

97%

form

solid

mp

190-193 °C (lit.)

SMILES string

CCOc1ccc2nc(sc2c1)S(N)(=O)=O

InChI

1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)

InChI key

OUZWUKMCLIBBOG-UHFFFAOYSA-N

Gene Information

human ... CA1(759) , CA12(771) , CA13(377677) , CA14(23632) , CA2(760) , CA3(761) , CA4(762) , CA5A(763) , CA5B(11238) , CA6(765) , CA7(766) , CA9(768)
mouse ... Car5a(12352)

Looking for similar products? Visit Product Comparison Guide

General description

6-Ethoxy-2-benzothiazolesulfonamide is a membrane permeable carbonic anhydrase inhibitor and its ocular disposition and pharmacology in normal albino rabbits has been investigated. It causes inhibition of insulin degradation in vitro.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCG0797
MKBL4148V
76896KJV
76896KJ
08305MH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Bernardo V Alvarez et al.
The Journal of physiology, 579(Pt 1), 127-145 (2006-11-25)
Hypertrophic cardiomyocyte growth contributes substantially to the progression of heart failure. Activation of the plasma membrane Na+-H+ exchanger (NHE1) and Cl- -HCO3- exchanger (AE3) has emerged as a central point in the hypertrophic cascade. Both NHE1 and AE3 bind carbonic
Claudia Höhne et al.
American journal of physiology. Lung cellular and molecular physiology, 292(1), L178-L184 (2006-08-29)
Acute hypoxic pulmonary vasoconstriction can be inhibited by high doses of the carbonic anhydrase inhibitor acetazolamide. This study aimed to determine whether acetazolamide is effective at dosing relevant to human use at high altitude and to investigate whether its efficacy
N A Tobey et al.
American journal of physiology. Gastrointestinal and liver physiology, 293(1), G264-G270 (2007-04-14)
The human esophagus is lined by stratified squamous epithelium (ESSE), and in some subjects with reflux disease the distal esophagus becomes lined by Barrett's specialized columnar epithelium (BSCE). ESSE and BSCE differ both histologically and functionally, the latter evident by
Jatinder Kaur et al.
Journal of medicinal chemistry, 63(17), 9540-9562 (2020-08-14)
Vancomycin-resistant enterococci (VRE) are the second leading cause of hospital-acquired infections (HAIs) attributed to a drug-resistant bacterium in the United States, and resistance to the frontline treatments is well documented. To combat VRE, we have repurposed the FDA-approved carbonic anhydrase
Holger M Becker et al.
The Journal of biological chemistry, 282(18), 13508-13521 (2007-03-14)
Several acid/base-coupled membrane transporters, such as the electrogenic sodium-bicarbonate cotransporter (NBCe1), have been shown to bind to different carbonic anhydrase isoforms to create a "transport metabolon." We have expressed NBCe1 derived from human kidney in oocytes of Xenopus leavis and
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service