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Merck
CN

332992

3-(4-Chlorophenyl)-1,1-dimethylurea

99%

Synonym(s):

Monuron

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About This Item

Linear Formula:
ClC6H4NHCON(CH3)2
CAS Number:
Molecular Weight:
198.65
EC Number:
205-766-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
2097922
MDL number:
Assay:
99%
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InChI key

BMLIZLVNXIYGCK-UHFFFAOYSA-N

InChI

1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)

SMILES string

CN(C)C(=O)Nc1ccc(Cl)cc1

assay

99%

mp

173-174 °C (lit.)

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

General description

3-(4-Chlorophenyl)-1,1-dimethylurea is an inhibitor of photophosphorylation. The kinetics of photo-induced transformation of 3-(4-chlorophenyl)-1,1-dimethylurea has been investigated in aqueous solution containing nitrates and nitrites at 310nm and 365nm. Degradation of Monuron (3-(4-chlorophenyl)-1,1-dimethylurea) photoinduced by Fe(III) in aqueous solution has been reported.

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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STOMATAL RESPONSES TO CHANGES IN CARBON DIOXIDE CONCENTRATION IN LEAVES TREATED WITH 3-(4-CHLOROPHENYL)-1, 1-DIMETHYLUREA.
Allaway WG and Mansfield TA.
The New phytologist, 66(1), 57-63 (1967)
L C Rai et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 5(1), 13-16 (1992-01-01)
The impact of 2,4-dinitrophenol and chlorophenyl dimethylurea on ATP content, carbon fixation, O2 evolution, nitrogenase activity and Cr uptake of Anabaena doliolum has been studied. 2,4-Dinitrophenol has been found to be more toxic than chlorophenyldimethylurea for all these processes. However
[Hygienic evaluation of translocation of the herbicides diuron and monuron].
L T Voloshina
Gigiena i sanitariia, (7)(7), 75-75 (1984-07-01)
Maria Bobu et al.
Chemosphere, 63(10), 1718-1727 (2005-11-18)
The photodegradation of monuron (3-(4-chlorophenyl)-1,1-dimethylurea) in aqueous solutions under simulated solar irradiation has been conducted by different advanced oxidation processes (UV/H(2)O(2), UV/H(2)O(2)/Fe(2+), UV/H(2)O(2)/TiO(2), UV/TiO(2), dark H(2)O(2)/Fe(3+)). The degradation rates were always higher for the homogeneous catalysis in photo-Fenton reactions (UV/H(2)O(2)/Fe(2+))
W Chu et al.
Journal of agricultural and food chemistry, 55(14), 5708-5713 (2007-06-15)
The immobilization of cobalt ion on different media to catalyze oxone has been investigated. A probe herbicide, Monuron, was effectively degraded by using Co2+/oxone systems. For Co2+ supported on zeolite, 100% of Monuron could be removed within a 10 min

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