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Merck
CN

327115

o-Toluidine hydrochloride

98%

Synonym(s):

2-Methylaniline hydrochloride

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About This Item

Linear Formula:
CH3C6H4NH2 · HCl
CAS Number:
Molecular Weight:
143.61
EC Number:
211-252-8
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3558629
MDL number:
Assay:
98%
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InChI key

OGVXWEOZQMAAIM-UHFFFAOYSA-N

InChI

1S/C7H9N.ClH/c1-6-4-2-3-5-7(6)8;/h2-5H,8H2,1H3;1H

SMILES string

Cl.Cc1ccccc1N

assay

98%

mp

215-217 °C (lit.)

General description

o-Toluidine hydrochloride is a demonstrated animal carcinogen.

Application

o-Toluidine hydrochloride was used in preparation of 9,9-bis(3-methyl-4-aminophenyl)fluorine.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Ortho alkyl substituents effect on solubility and thermal properties of fluorenyl cardo polyimides.
Hu Z, et al.
Polymer, 46(14), 5278-5283 (2005)
M Elwell
Toxicity report series, 44, 1-C8-1-C8 (2002-07-16)
o-Nitrotoluene and o-toluidine hydrochloride are structurally related chemicals that are suspected and demonstrated animal carcinogens, respectively. The metabolic potential of the gastrointestinal flora is considered an important factor in o-nitrotoluene-induced toxicity and involves the reduction of the nitro group to
Qishu Qu et al.
Se pu = Chinese journal of chromatography, 28(3), 260-263 (2010-06-17)
Bare nonporous silica particles with diameter around 1 microm were prepared. A 20 cm section of a total length of 45 cm capillary (100 microm i. d.) was packed electrokinetically and the separation performance of basic compounds was investigated in
o‑Toluidine and its hydrochloride.
Report on carcinogens : carcinogen profiles, 12, 416-418 (2011-08-25)
Emna Hmani et al.
Journal of hazardous materials, 170(2-3), 928-933 (2009-06-23)
Electrochemical oxidation of O-toluidine (OT) was studied by galvanostatic electrolysis using lead dioxide (PbO2) and boron-doped diamond (BDD) as anodes. The influence of operating parameters, such as current density, initial concentration of OT and temperature was investigated. Measurements of chemical

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