316539
1,8-Naphthosultone
98%
Synonym(s):
1-Naphthol-8-sulfonic acid sultone, 8-Hydroxynaphthalene-1-sulfonic acid sultone
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C10H6O3S
CAS Number:
Molecular Weight:
206.22
Beilstein:
9381
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
form
solid
mp
154-157 °C (dec.) (lit.)
functional group
sulfonic acid
SMILES string
O=S1(=O)Oc2cccc3cccc1c23
InChI
1S/C10H6O3S/c11-14(12)9-6-2-4-7-3-1-5-8(13-14)10(7)9/h1-6H
InChI key
IEIADDVJUYQKAZ-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Sébastien Schmitt et al.
Chemical communications (Cambridge, England), 47(41), 11465-11467 (2011-09-29)
Sultones were subject to ring opening by nucleophilic attack with [(18)F]fluoride to afford easily purified (18)F-labelled hydrophilic sulfonated products in high yields. A two-step sequence including radiofluorination and coupling to lysine was then developed from a bis-sultone precursor as a
Sonia De Castro et al.
Journal of medicinal chemistry, 52(6), 1582-1591 (2009-02-20)
We report the synthesis and antiviral activity of a new family of non-nucleoside antivirals, derived from the 4-keto-1,2-oxathiole-2,2-dioxide (beta-keto-gamma-sultone) heterocyclic system. Several 4- and 5-substituted-5H-1,2-oxathiole-2,2-dioxide derivatives were found to have a selective inhibitory activity against human cytomegalovirus (HCMV) and varicella
Single injection adjuvant test.
B F Goodwin et al.
Current problems in dermatology, 14, 201-207 (1985-01-01)
Scott A Wolckenhauer et al.
Organic letters, 9(21), 4363-4366 (2007-09-25)
Rhodium-catalyzed reactions of sulfonate ester derivatives are biased strongly toward 1,6-insertion and thus offer a general method for assembling delta-sultones. Two protocols for staging this cyclization reaction are described, which capitalize on the unique ability of either diazo or iodonium
Donald C Craig et al.
Carbohydrate research, 346(6), 854-857 (2011-03-11)
Acetolysis of methyl 5,6-di-O-acetyl-2,3-O-isopropylidene-β-L-gulofuranoside has yielded a sultone, 4-(1,2,5,6-tetra-O-acetyl-β-L-gulofuranos-3-yl)-6-methyl-1,2-oxathiin 2,2-dioxide (2) whose structure was determined by X-ray diffraction. (1)H and (13)C NMR spectral properties of 2 are presented together with a rationale for its formation. Preparation and properties of the
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