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Key Documents

Safety Information

308129

Sigma-Aldrich

N-Methyldibutylamine

98%

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About This Item

Linear Formula:
[CH3(CH2)3]2NCH3
CAS Number:
Molecular Weight:
143.27
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.4178 (lit.)

bp

49-51 °C/10 mmHg (lit.)

density

0.745 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

CCCCN(C)CCCC

InChI

1S/C9H21N/c1-4-6-8-10(3)9-7-5-2/h4-9H2,1-3H3

InChI key

MTHFROHDIWGWFD-UHFFFAOYSA-N

Application

N-Methyldibutylamine was used to identify a series of optimized mobile phase systems with 25 to 50mM hexafluoroisopropanol that yielded high MS signal intensity for both siRNA and DNA.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

107.6 °F - closed cup

Flash Point(C)

42 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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A Cary McGinnis et al.
Rapid communications in mass spectrometry : RCM, 27(23), 2655-2664 (2014-03-05)
New methods to enhance the electrospray ionization (ESI) signals are essential for low-level analysis of oligonucleotides. We report a systematic evaluation comparing 13 ion-pairing agents with and without hexafluoroisopropanol to understand their effect on the ion abundance of hetero-oligonucleotides. A
Jaeah Kim et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1124, 247-255 (2019-06-27)
Understanding the mechanisms underlying cancer cell survival is critical toward advancing drug discovery efforts in this field. Supplemental vitamins have been proposed to play a role in cancer cell metabolism because the increased supply of nutrients is thought to provide
J Michael Sutton et al.
Rapid communications in mass spectrometry : RCM, 34(8), e8696-e8696 (2019-12-14)
Cationic adduction causes poor sensitivity and increases spectral complexity during mass spectral analysis of oligonucleotides and alkylamines are used to reduce this adduction. It is unclear the effect of the physiochemical properties of the alkylamines on the reduction of the

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