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Assay
98%
form
liquid
refractive index
n20/D 1.4178 (lit.)
bp
49-51 °C/10 mmHg (lit.)
density
0.745 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
CCCCN(C)CCCC
InChI
1S/C9H21N/c1-4-6-8-10(3)9-7-5-2/h4-9H2,1-3H3
InChI key
MTHFROHDIWGWFD-UHFFFAOYSA-N
Application
N-Methyldibutylamine was used to identify a series of optimized mobile phase systems with 25 to 50mM hexafluoroisopropanol that yielded high MS signal intensity for both siRNA and DNA.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
107.6 °F - closed cup
Flash Point(C)
42 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Rapid communications in mass spectrometry : RCM, 27(23), 2655-2664 (2014-03-05)
New methods to enhance the electrospray ionization (ESI) signals are essential for low-level analysis of oligonucleotides. We report a systematic evaluation comparing 13 ion-pairing agents with and without hexafluoroisopropanol to understand their effect on the ion abundance of hetero-oligonucleotides. A
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1124, 247-255 (2019-06-27)
Understanding the mechanisms underlying cancer cell survival is critical toward advancing drug discovery efforts in this field. Supplemental vitamins have been proposed to play a role in cancer cell metabolism because the increased supply of nutrients is thought to provide
Rapid communications in mass spectrometry : RCM, 34(8), e8696-e8696 (2019-12-14)
Cationic adduction causes poor sensitivity and increases spectral complexity during mass spectral analysis of oligonucleotides and alkylamines are used to reduce this adduction. It is unclear the effect of the physiochemical properties of the alkylamines on the reduction of the
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