307882
(R)-(−)-2-Phenylglycine methyl ester hydrochloride
≥95%
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C6H5CH(NH2)CO2CH3·HCl
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Assay
≥95%
form
solid
optical activity
[α]20/D −118°, c = 1 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
189-191 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl.COC(=O)[C@H](N)c1ccccc1
InChI
1S/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/m1./s1
InChI key
DTHMTBUWTGVEFG-DDWIOCJRSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Bioscience, biotechnology, and biochemistry, 61(10), 1783-1785 (1997-11-15)
The absolute configuration of pectenotoxin-6 (4, PTX6), found in association with diarrhetic shellfish poisoning, was identified by NMR spectroscopy using a chiral anisotropic reagent, phenylglycine methyl ester (PGME), which was condensed with a carboxyl group of 4.
Biochemistry. Biokhimiia, 65(12), 1367-1375 (2001-02-15)
Kinetic regularities of the enzymatic acyl group transfer reactions have been studied using ampicillin synthesis catalyzed by E. coli penicillin acylase as an example. It was shown that ampicillin synthesis proceeds through the formation of an acylenzyme-nucleophile complex capable of
Journal of hazardous materials, 146(3), 440-446 (2007-05-29)
This paper reports on the combined solar photo-Fenton/biological treatment of an industrial effluent (initial total organic carbon, TOC, around 500mgL(-1)) containing a non-biodegradable organic substance (alpha-methylphenylglycine at 500mgL(-1)), focusing on pilot plant tests performed for design of an industrial plant
Protein engineering, design & selection : PEDS, 17(7), 571-579 (2004-08-31)
A semi-random mutagenesis approach was followed to increase the performance of penicillin acylase PAS2 in the kinetically controlled synthesis of ampicillin from 6-aminopenicillanic acid (6-APA) and activated D-phenylglycine derivatives. We directed changes in amino acid residues to positions close to
Antibiotiki, 26(12), 920-932 (1981-12-01)
The possible use of various procedures for estimation of the ionization constants of the Michaelis complex by the pH dependence of the maximum enzymatic reaction rate is discussed. It is shown that the procedures described in the literature for estimation
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