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307882

Sigma-Aldrich

(R)-(−)-2-Phenylglycine methyl ester hydrochloride

≥95%

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Linear Formula:
C6H5CH(NH2)CO2CH3·HCl
CAS Number:
Molecular Weight:
201.65
EC Number:
MDL number:
UNSPSC Code:
12352200
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Assay

≥95%

form

solid

optical activity

[α]20/D −118°, c = 1 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

189-191 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.COC(=O)[C@H](N)c1ccccc1

InChI

1S/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/m1./s1

InChI key

DTHMTBUWTGVEFG-DDWIOCJRSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K Sasaki et al.
Bioscience, biotechnology, and biochemistry, 61(10), 1783-1785 (1997-11-15)
The absolute configuration of pectenotoxin-6 (4, PTX6), found in association with diarrhetic shellfish poisoning, was identified by NMR spectroscopy using a chiral anisotropic reagent, phenylglycine methyl ester (PGME), which was condensed with a carboxyl group of 4.
M I Youshko et al.
Biochemistry. Biokhimiia, 65(12), 1367-1375 (2001-02-15)
Kinetic regularities of the enzymatic acyl group transfer reactions have been studied using ampicillin synthesis catalyzed by E. coli penicillin acylase as an example. It was shown that ampicillin synthesis proceeds through the formation of an acylenzyme-nucleophile complex capable of
Sixto Malato et al.
Journal of hazardous materials, 146(3), 440-446 (2007-05-29)
This paper reports on the combined solar photo-Fenton/biological treatment of an industrial effluent (initial total organic carbon, TOC, around 500mgL(-1)) containing a non-biodegradable organic substance (alpha-methylphenylglycine at 500mgL(-1)), focusing on pilot plant tests performed for design of an industrial plant
Esther M Gabor et al.
Protein engineering, design & selection : PEDS, 17(7), 571-579 (2004-08-31)
A semi-random mutagenesis approach was followed to increase the performance of penicillin acylase PAS2 in the kinetically controlled synthesis of ampicillin from 6-aminopenicillanic acid (6-APA) and activated D-phenylglycine derivatives. We directed changes in amino acid residues to positions close to
P S Nys et al.
Antibiotiki, 26(12), 920-932 (1981-12-01)
The possible use of various procedures for estimation of the ionization constants of the Michaelis complex by the pH dependence of the maximum enzymatic reaction rate is discussed. It is shown that the procedures described in the literature for estimation

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