302309
2-Cyanoethyl N,N-diisopropylchlorophosphoramidite
Cl 13.5-15.5 %
Synonym(s):
Chloro(diisopropylamino)-β-cyanoethoxyphosphine
About This Item
form
liquid
Quality Level
composition
Cl, 13.5-15.5%
density
1.061 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
CC(C)N(C(C)C)P(Cl)OCCC#N
InChI
1S/C9H18ClN2OP/c1-8(2)12(9(3)4)14(10)13-7-5-6-11/h8-9H,5,7H2,1-4H3
InChI key
QWTBDIBOOIAZEF-UHFFFAOYSA-N
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Application
- for selective monophosphorylation of carbohydrates and nucleosides
- for conversion of protected ribonucleosides to phosphoramidites
- as phosphitylating reagent for 3′-hydroxyl groups in the synthesis of oligodeoxyribonucleotides
- in a scalable, solution-phase oligonucleotide synthesis employing phosphoramidite chemistry and DMT-, iBu- and Bz-protected monomers. Intermediates were isolated by extraction without further purification
related product
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Pyr. Liq. 1 - Skin Corr. 1B
WGK
WGK 3
Flash Point(F)
230.0 °F
Flash Point(C)
110 °C
Personal Protective Equipment
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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