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297747

Sigma-Aldrich

3,6-Dichloro-4-methylpyridazine

97%

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Empirical Formula (Hill Notation):
C5H4Cl2N2
CAS Number:
Molecular Weight:
163.00
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

bp

149-151 °C/21 mmHg (lit.)

mp

86-88 °C (lit.)

SMILES string

Cc1cc(Cl)nnc1Cl

InChI

1S/C5H4Cl2N2/c1-3-2-4(6)8-9-5(3)7/h2H,1H3

InChI key

ROYHWGZNGMXQEU-UHFFFAOYSA-N

Application

3,6-Dichloro-4-methylpyridazine has been used in the synthesis of 7-methyl-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Maria Grazia Rimoli et al.
Neuropharmacology, 56(3), 637-646 (2008-12-17)
It is presently unclear whether the antiseizure effects exerted by NSAIDs are totally dependent on COX inhibition or not. To clarify this point we investigated whether 7-methyl-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid (DM1) and 6-methoxy-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid (DM2), two imidazo[1,2-b]pyridazines structurally related to indomethacin (IDM)

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