293369
3-Aminopiperidine dihydrochloride
97%
Synonym(s):
3-Piperidinamine dihydrochloride
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About This Item
Empirical Formula (Hill Notation):
C5H12N2 · 2HCl
Molecular Weight:
173.08
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Assay
97%
form
solid
mp
230 °C (dec.) (lit.)
SMILES string
Cl.Cl.NC1CCCNC1
InChI
1S/C5H12N2.2ClH/c6-5-2-1-3-7-4-5;;/h5,7H,1-4,6H2;2*1H
InChI key
GGPNYXIOFZLNKW-UHFFFAOYSA-N
General description
Estimation of (S)-piperidin-3-amine in (R)-piperidin-3-amine dihydrochloride (3-aminopiperidine dihydrochloride) has been investigated by chiral high-performance liquid chromatographic (chiral HPLC) method.
Application
Reactant for N-arylation of heterocyclic diamines
Reactant for synthesis of substituted quinolones with reduced phototoxic risk
Reactant for synthesis of substituted quinolones with reduced phototoxic risk
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Shubo Dong et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 33(3), 293-298 (2017-03-18)
A sensitive non-derivatization method for the determination of the highly polar compound 3-aminopiperidine was developed using a mixed-mode column combined with a charged aerosol detector (CAD). Chromatographic conditions, including the type of detector, separation mode, and mobile phase composition, were
Chittabathina Venkata Raghunadha Babu et al.
Chirality, 26(12), 775-779 (2014-07-22)
A simple, precise, accurate, robust chiral high-performance liquid chromatographic (chiral HPLC) method was developed for estimation of (S)-piperidin-3-amine (S-isomer) in (R)-piperidin-3-amine dihydrochloride (R-AMP). As AMP is a high-melting solid and nonchromophoric compound, development of a suitable chiral method is a
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