286567
Mephenesin
98%
Synonym(s):
3-(2-Methylphenoxy)-1,2-propanediol
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About This Item
Linear Formula:
CH3C6H4OCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
182.22
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
200-427-4
MDL number:
Assay:
98%
Form:
powder
InChI key
JWDYCNIAQWPBHD-UHFFFAOYSA-N
InChI
1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3
SMILES string
Cc1ccccc1OCC(O)CO
assay
98%
form
powder
bp
153-154 °C/4 mmHg (lit.)
mp
69-71 °C (lit.)
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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C Bachmeyer et al.
Annales de dermatologie et de venereologie, 123(3), 185-187 (1996-01-01)
Mephenesin is a muscle relaxant, mostly applied locally in trauma. It is a component of Traumalgyl cream in association with phenylbutazone. Contact dermatitis due to mephenesin is exceptional. We report here a case of a woman who developed after application
B Nickel et al.
Arzneimittel-Forschung, 40(8), 909-911 (1990-08-01)
The influence of the skeletal muscle tone by flupirtine (D-9998, Katadolon; CAS 56995-20-1), some selected analgesics and muscle relaxants was investigated in conscious rats after intraperitoneal administration. Benzodiazepines (diazepam and tetrazepam), baclofen, dantrolene and mephenesine reduced the tone of the
Karolina Szokol et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(12), 4731-4742 (2011-03-25)
The medullary reticular formation (MRF) of the neonatal mouse is organized so that the medial and lateral MRF activate hindlimb and trunk motoneurons (MNs) with differential predominance. The goal of the present study was to investigate whether this activation is
Laurent Fanton et al.
Journal of forensic sciences, 52(1), 221-223 (2007-01-11)
This report describes a death related to the abuse of and intoxication by mephenesin. To the best of our knowledge, this is the first report case of lethal intoxication involving solely mephenesin and reporting mephenesin blood concentrations. The victim was
C Beltran et al.
Annales de dermatologie et de venereologie, 136(10), 709-712 (2009-10-06)
In most cases, acute generalized exanthematous pustulosis (AGEP) is a drug reaction. Even if several systemic drugs have been reported to be a causative agent, this clinical case has rarely been observed with a topical treatment. We report here a
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