285943
β-D-Glucose pentaacetate
98%
Synonym(s):
beta-D-Glucose pentaacetate, 1,2,3,4,6-Penta-O-acetyl-β-D-glucopyranose
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About This Item
Empirical Formula (Hill Notation):
C16H22O11
CAS Number:
Molecular Weight:
390.34
UNSPSC Code:
12352201
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-074-8
Beilstein/REAXYS Number:
98851
MDL number:
InChI key
LPTITAGPBXDDGR-IBEHDNSVSA-N
InChI
1S/C16H22O11/c1-7(17)22-6-12-13(23-8(2)18)14(24-9(3)19)15(25-10(4)20)16(27-12)26-11(5)21/h12-16H,6H2,1-5H3/t12-,13-,14+,15-,16-/m1/s1
SMILES string
CC(O)O[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
assay
98%
form
powder
optical activity
[α]20/D +4.2°, c = 1 in chloroform
mp
130-132 °C (lit.)
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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Insulinotropic action of monosaccharide esters: therapeutic perspectives.
W J Malaisse
Diabetologia, 42(3), 286-291 (1999-03-30)
Directed assembly of sub-nanometer thin organic materials with programmed-size nanopores.
Delia C Danila et al.
Angewandte Chemie (International ed. in English), 47(37), 7036-7039 (2008-08-05)
K Louchami et al.
International journal of molecular medicine, 3(2), 181-184 (1999-01-26)
The anomers of both D-glucose pentaacetate and L-glucose pentaacetate were recently found to display insulinotropic potential. In order to progress in understanding the mode of action of these esters in islet cells, we have now investigated whether they mimic the
Monosaccharide esters: clinically relevant?
E O Balasse
Acta clinica Belgica, 57(2), 47-48 (2002-08-03)
L Ladriere et al.
International journal of molecular medicine, 5(4), 331-333 (2000-03-17)
Tumoral pancreatic islet cells of the RINm5F line were incubated, in groups of 25x106 cells each, for 120 min at 37 degrees C in media (5. 0 ml) containing either alpha-D-[1,2-13C]glucose pentaacetate (1.7 mM) or both D-[1,2-13C]glucose (1.7 mM) and
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