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Merck
CN

283215

Poly(allylamine hydrochloride)

average Mw ~17,500 (GPC vs. PEG std.)

Synonym(s):

PAA HCl, PAH

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About This Item

Linear Formula:
[CH2CH(CH2NH2 · HCl)]n
CAS Number:
71550-12-4
NACRES:
NA.23
PubChem Substance ID:
24857093
UNSPSC Code:
12162002
EC Number:
415-050-2
MDL number:
MFCD00084396

Key Documents

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Product Name

Poly(allylamine hydrochloride), average Mw ~17,500 (GPC vs. PEG std.)

InChI key

VVJKKWFAADXIJK-UHFFFAOYSA-N

InChI

1S/C3H7N/c1-2-3-4/h2H,1,3-4H2

SMILES string

Cl.NCC=C

form

solid

mol wt

average Mw ~17,500 (GPC vs. PEG std.)

Quality Level

200

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Application

Poly(allylamine hydrochloride) can be used as a starting material to prepare:
  • Chitosan/PAH polymer blend films by solution casting technique. These films can be employed in injectable drug delivery systems and tissue generation.
  • Cross-linked amino-modified graphene oxide for the removal of Cr(IV) from aqueous solutions.
  • Polyelectrolyte multilayers(PEMs) by the layer-by-layer method. These PEMs can be used to prepare controlled drug delivery systems and coatings with controlled cell adhesion properties.
Used to make redox hydrogel-modified electrodes for measuring enzyme responses.

Features and Benefits

  • Excellent environmental stability
  • Water-soluble
  • Low cost

General description

Poly(allylamine hydrochloride) (PAH) is a water-soluble weak-base and a biodegradable polymer.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW9342
MKCX9141
MKCX7578
0000416416
0000416416

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L Minati et al.
International journal of pharmaceutics, 438(1-2), 45-52 (2012-09-11)
Gold nanoparticles functionalized with doxorubicin and stabilized with multilayers of degradable polyelectrolyte were allowed to age in aqueous medium in vitro in order to show the possibility of drug release in cellular environment. The chemico-physical characteristics of the nanoparticles are
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Chemistry, an Asian journal, 8(2), 385-391 (2012-12-12)
Multimodal imaging and simultaneous therapy is highly desirable because it can provide complementary information from each imaging modality for accurate diagnosis and, at the same time, afford an imaging-guided focused tumor therapy. In this study, indocyanine green (ICG), a near-infrared
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International journal of nanomedicine, 7, 4037-4051 (2012-08-14)
We designed dual-functional nanoparticles for in vivo application using a modified electrostatic and covalent layer-by-layer assembly strategy to address the challenge of assessment and treatment of hormone-refractory prostate cancer. Core-shell nanoparticles were formulated by integrating three distinct functional components, ie
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Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

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