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Sigma-Aldrich

Poly(allylamine hydrochloride)

average Mw ~17,500 (GPC vs. PEG std.)

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Synonym(s):
PAA HCl, PAH
Linear Formula:
[CH2CH(CH2NH2 · HCl)]n
CAS Number:
71550-12-4
EC Number:
415-050-2
MDL number:
MFCD00084396
UNSPSC Code:
12162002
PubChem Substance ID:
24857093
NACRES:
NA.23

form

solid

Quality Level

200

mol wt

average Mw ~17,500 (GPC vs. PEG std.)

SMILES string

Cl.NCC=C

InChI

1S/C3H7N/c1-2-3-4/h2H,1,3-4H2

InChI key

VVJKKWFAADXIJK-UHFFFAOYSA-N

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General description

Poly(allylamine hydrochloride) (PAH) is a water-soluble weak-base and a biodegradable polymer.

Application

Poly(allylamine hydrochloride) can be used as a starting material to prepare:
  • Chitosan/PAH polymer blend films by solution casting technique. These films can be employed in injectable drug delivery systems and tissue generation.
  • Cross-linked amino-modified graphene oxide for the removal of Cr(IV) from aqueous solutions.
  • Polyelectrolyte multilayers(PEMs) by the layer-by-layer method. These PEMs can be used to prepare controlled drug delivery systems and coatings with controlled cell adhesion properties.
Used to make redox hydrogel-modified electrodes for measuring enzyme responses.

Features and Benefits

  • Excellent environmental stability
  • Water-soluble
  • Low cost

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xin Gao et al.
International journal of nanomedicine, 7, 4037-4051 (2012-08-14)
We designed dual-functional nanoparticles for in vivo application using a modified electrostatic and covalent layer-by-layer assembly strategy to address the challenge of assessment and treatment of hormone-refractory prostate cancer. Core-shell nanoparticles were formulated by integrating three distinct functional components, ie
Magdalena Oćwieja et al.
Langmuir : the ACS journal of surfaces and colloids, 29(11), 3546-3555 (2013-01-17)
Systematic studies of silver particle deposition kinetics under diffusion transport on poly(allylamine hydrochloride) (PAH) modified mica were carried out. Monolayer coverage, quantitatively determined by AFM and SEM, was regulated within broad limits by adjusting the deposition time and the ionic
Ya Wang et al.
Macromolecular bioscience, 12(10), 1321-1325 (2012-09-12)
Fluorescent-magnetic-biotargeting multifunctional microcapsules (FMBMMs) are designed and fabricated via layer-by-layer assembly. It is found that the arginine-glycine-aspartate-modified FMBMMs were capable of sensitively detecting and efficiently isolating approximately 80% target cancer cells within 20 min. More importantly, FMBMMs present a general
B Marzec et al.
Journal of structural biology, 208(2), 127-136 (2019-08-23)
Coccolithophores are marine phytoplankton that are among the most prolific calcifiers widespread in Earth's oceans, playing a crucial role in the carbon cycle and in the transport of organic matter to the deep sea. These organisms produce highly complex mineralized
Farida Akhatova et al.
Bio-protocol, 7(21), e2596-e2596 (2017-11-05)
The free-living soil nematode Caenorhabditis elegans has become an iconic experimental model animal in biology. This transparent animal can be easily imaged using optical microscopy to visualise its organs, tissues, single cells and subcellular events. The epicuticle of C. elegans
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Articles

Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

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