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Merck
CN

282553

(1R,2S)-(−)-Norephedrine

99%

Synonym(s):

(1R,2S)-2-Amino-1-phenyl-1-propanol, L-(−)-Norephedrine

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About This Item

Linear Formula:
C6H5CH(OH)CH(CH3)NH2
CAS Number:
Molecular Weight:
151.21
EC Number:
207-755-7
UNSPSC Code:
12352116
PubChem Substance ID:
Beilstein/REAXYS Number:
2207678
MDL number:
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Product Name

(1R,2S)-(−)-Norephedrine, 99%

form

solid

assay

99%

InChI key

DLNKOYKMWOXYQA-CBAPKCEASA-N

InChI

1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m0/s1

SMILES string

C[C@H](N)[C@H](O)c1ccccc1

optical activity

[α]20/D −41°, c = 7 in 1 M HCl

mp

51-53 °C (lit.)

storage temp.

2-8°C

Gene Information

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Susan A Adeoya-Osiguwa et al.
Human reproduction (Oxford, England), 20(1), 198-207 (2004-10-30)
Cathinone, released when Catha edulis leaves (khat) are chewed, has euphoric, stimulatory properties. It is metabolized to the phenylpropanolamines (PPAs) cathine and norephedrine. This study investigated whether PPAs affect mammalian sperm function, using primarily mouse, but also human, spermatozoa. Uncapacitated
K Deventer et al.
Drug testing and analysis, 1(5), 209-213 (2010-04-01)
Until the end of 2003 a urinary concentration of pseudoephedrine exceeding 25 microg/mL was regarded as a doping violation by the World Anti-Doping Agency. Since its removal from the prohibited list in 2004 the number of urine samples in which
Veniero Gambaro et al.
Forensic science international, 217(1-3), 87-92 (2011-10-26)
In the last years, all the vegetable material supposed to belong to the Catha Edulis species, seized at the Malpensa and Orio al Serio airports, were analyzed in our laboratory on behalf of the Tribunals of Busto Arsizio and Bergamo
Li Huang et al.
Journal of AOAC International, 87(5), 1058-1062 (2004-10-21)
The use of a single internal standard (ephedrine-d5) as the basis for calculations of the concentrations of both the major and the minor alkaloids leads to incorrect results from variabilities in the solid-phase extraction (SPE) of the ephedra alkaloids. Because
Richard Hoffman et al.
Journal of ethnopharmacology, 132(3), 554-563 (2010-06-18)
Although there is a rich body of research available regarding the effect of acute and chronic khat dosing in animal models, research on the behavioral and cognitive effects of khat in human subjects is not extensive and several of the

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