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Sigma-Aldrich

Carvacrol

98%

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Synonym(s):
5-Isopropyl-2-methylphenol
Linear Formula:
(CH3)2CHC6H3(CH3)OH
CAS Number:
499-75-2
Molecular Weight:
150.22
Beilstein:
1860514
EC Number:
207-889-6
MDL number:
MFCD00002236
UNSPSC Code:
12352100
PubChem Substance ID:
24857025
NACRES:
NA.22

Quality Level

100

Assay

98%

form

liquid

refractive index

n20/D 1.522 (lit.)

bp

236-237 °C (lit.)

mp

3-4 °C (lit.)

density

0.976 g/mL at 20 °C (lit.)

SMILES string

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

InChI key

RECUKUPTGUEGMW-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

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General description

Carvacrol is a monoterpenic phenol produced by aromatic plants, thyme and oregano. Carvacrol has been evaluated as alternatives to antibiotic feed additives in female broiler chickens.

Application

Carvacrol has been used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Signal Word

Danger

Hazard Statements

H302,H314,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Ultee et al.
Journal of applied microbiology, 85(2), 211-218 (1998-09-29)
Carvacrol, a natural plant constituent occurring in oregano and thyme, was investigated for its bactericidal effect towards the food-borne pathogen Bacillus cereus. Carvacrol showed a dose-related growth inhibition of B. cereus. At concentration of 0.75 mmol l-1 and above, total
Antibacterial activity of carvacrol, citral, and geraniol against Salmonella typhimurium in culture medium and on fish cubes.
Kim JM, et al.
Journal of Food Science, 60(6), 1364-1368 (1995)
S Ananda Baskaran et al.
Journal of dairy science, 92(4), 1423-1429 (2009-03-25)
The objective of this study was to investigate the antimicrobial effect of plant-derived antimicrobials including trans-cinnamaldehyde (TC), eugenol, carvacrol, and thymol on major bacterial mastitis pathogens in milk. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the
Dietary carvacrol lowers body weight gain but improves feed conversion in female broiler chickens.
Lee K-W, et al.
The Journal of Applied Poultry Research, 12(4), 394-399 (2003)
Zacharias E Suntres et al.
Critical reviews in food science and nutrition, 55(3), 304-318 (2014-06-11)
Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants, including thyme and oregano. Presently, carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations.
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