Skip to Content
Merck
CN

280135

2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide

Dye content 95 %

Synonym(s):

2-Di-1-ASP

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C16H19IN2
CAS Number:
2156-29-8
Molecular Weight:
366.24
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
57648287
EC Number:
218-460-8
Beilstein/REAXYS Number:
3776369
MDL number:
MFCD00011980

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide, Dye content 95 %

InChI key

XPOIQAIBZGSIDD-UHFFFAOYSA-M

InChI

1S/C16H19N2.HI/c1-17(2)15-10-7-14(8-11-15)9-12-16-6-4-5-13-18(16)3;/h4-13H,1-3H3;1H/q+1;/p-1

SMILES string

[I-].CN(C)c1ccc(cc1)\C=C\c2cccc[n+]2C

form

solid

composition

Dye content, 95%

mp

280 °C (dec.) (lit.)

λmax

466 nm

fluorescence

λex 466 nm; λem 504 nm in methanol
λex 475 nm; λem 589 nm in methanol

Looking for similar products? Visit Product Comparison Guide

Application

DASPMI is a polar sensitive dye that measures the membrane potential of mitochondria in living cells. It may be used as a light absorber in the development of a photoinitiator based system.
DASPMI is popularly used in selective staining of mitochondria in living cells.

General description

2-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide (DASPMI) is a mitochondria staining styryl dye that is used to generate a quick responsive mechanism by applying changes in transmembrane potential. DASPMI can be used as a low toxic stain that shows a fluorescent behavior for mitochondria.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCL8555
MKBR0101V
04305MX
11620DD

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mitochondrial Function Is Involved in LDL Oxidation Mediated by Human Cultured Endothelial Cells
Mabile L, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 17, 1575-1582 (1997)
Anamika Manna et al.
The journal of physical chemistry. B, 116(8), 2464-2471 (2012-02-07)
We report an interesting pH-tunable energy transfer between an acceptor ionic styryl dye 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide and a donor charge-transfer dye 1,8-naphthalimide in a vesicular medium. The polyethylene-b-polyethylene glycol block copolymer intercalates with the sodium dodecyl sulfate anionic surfactant to form
Spectral signature of 2-[4-(dimethylamino) styryl]-1-methylquinolinium iodide: A case of negative solvatochromism in water
Sahoo D, et al.
The Journal of Physical Chemistry B, 115(37), 10983-10989 (2011)
Anamika Manna et al.
The journal of physical chemistry. B, 116(17), 5226-5233 (2012-04-18)
This paper reports an interesting transformation of binding mode of 2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide (DASPMI) with calf thymus DNA from minor groove binding in buffer solution to intercalative binding when the dye is encapsulated inside a vesicle formed by the interaction of
S C Chang et al.
The Journal of biological chemistry, 273(24), 14933-14941 (1998-06-17)
In eukaryotic cells, cardiolipin (CL) synthase catalyzes the final step in the synthesis of CL from phosphatidylglycerol and CDP-diacylglycerol. CL and its synthesis are localized predominantly to the mitochondrial inner membrane, and CL is generally thought to be an essential
View All Related Papers

Articles

Graphene in Biotechnology

Graphene is the building block for carbon nanomaterials with different dimensionalities.

Fluorescence Quenching Microscopy

Fluorescence quenching microscopy visualizes 2D materials like graphene and MoS2 rapidly, inexpensively, and with high fidelity.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service