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27815

Sigma-Aldrich

p-Toluenesulfonic acid monohydrate

≥99% (calc. to H2O free subst.)

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Synonym(s):
4-Methylbenzenesulfonic acid monohydrate, 4-Toluenesulfonic acid monohydrate, PTSA monohydrate, TsOH monohydrate
Linear Formula:
CH3C6H5SO3H · H2O
CAS Number:
6192-52-5
Molecular Weight:
190.22
Colour Index Number:
42655
Beilstein:
3568023
EC Number:
203-180-0
MDL number:
MFCD00142137
UNSPSC Code:
12352106
PubChem Substance ID:
57648235
NACRES:
NA.22

Quality Level

200

Assay

≥99% (calc. to H2O free subst.)

form

solid

impurities

≥85% toluene-4-solfonic acid
8-12% water (Karl Fischer)

ign. residue

≤0.5%

SMILES string

O.Cc1ccc(cc1)S(O)(=O)=O

InChI

1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2

InChI key

KJIFKLIQANRMOU-UHFFFAOYSA-N

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General description

p-Toluenesulfonic acid monohydrate, an oxonium salt, is an inexpensive and easy-to-handle organic catalyst used in organic synthesis.

Application

p-Toluenesulfonic acid monohydrate is a catalyst in esterification, reductive amination, Biginelli reaction, and intermolecular coupling of the aromatic nucleus. It is also used in the preparation of various bioactive compounds via multicomponent condensation reactions.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

危险化学品

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