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Sigma-Aldrich

Palmitic acid

≥98% palmitic acid basis (GC)

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Synonym(s):
1-Pentadecanecarboxylic acid, C16:0, Cetylic acid, Hexadecanoic acid, NSC 5030, PamOH
Linear Formula:
CH3(CH2)14COOH
CAS Number:
57-10-3
Molecular Weight:
256.42
Beilstein:
607489
EC Number:
200-312-9
MDL number:
MFCD00002747
UNSPSC Code:
12352100
PubChem Substance ID:
57648272
NACRES:
NA.21

vapor pressure

10 mmHg ( 210 °C)

Quality Level

200

Assay

≥98% palmitic acid basis (GC)

form

flakes
powder or crystals

technique(s)

gas chromatography (GC): suitable
thin layer chromatography (TLC): suitable

impurities

≤1% stearic acid (GC)

bp

271.5 °C/100 mmHg (lit.)

mp

61-62.5 °C (lit.)
62-65 °C

acid value

≤240

iodine value

≤0.5

saponification value

≤240

density

0.852 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCCCCCCCC(O)=O

InChI

1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)

InChI key

IPCSVZSSVZVIGE-UHFFFAOYSA-N

Gene Information

human ... FABP2(2169) , FABP3(2170) , FABP4(2167) , FABP5(2171)

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General description

Palmiticacid (C16:0) is a saturated fatty acid commonly found in various naturalsources, such as animal fats and plant oils.

Application

Palmitic acid may be employed in the preparation of palmitic anhydride, via reaction with dicyclohexylcarbodiimide (DCC) in carbon tetrachloride. It undergoes deoxygenation in the presence of 4%wt Pd/C mesoporous catalyst at 300°C and pressure of 17bar of 5% H2 in argon. Aliphatic chain length hydrocarbons containing one less carbon than the corresponding acid were obtained as major products.

WGK

nwg

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Catalytic deoxygenation of stearic acid and palmitic acid in semibatch mode.
Lestari S, et al.
Catalysis Letters, 130(1-2), 48-51 (2009)
Z Selinger et al.
Journal of lipid research, 7(1), 174-175 (1966-01-01)
A simple method is described for the preparation of caprylic, palmitic, stearic, and oleic anhydrides. Reaction of the free fatty acid and dicyclohexylcarbodiimide in carbon tetrachloride at room temperature gives the corresponding anhydrides in high yield (87-94%).
Xiaozhe Yin et al.
Cell reports, 33(3), 108278-108278 (2020-10-22)
Dendritic cells (DCs) orchestrate the initiation, programming, and regulation of anti-tumor immune responses. Emerging evidence indicates that the tumor microenvironment (TME) induces immune dysfunctional tumor-infiltrating DCs (TIDCs), characterized with both increased intracellular lipid content and mitochondrial respiration. The underlying mechanism
B Vessby et al.
Diabetologia, 37(10), 1044-1050 (1994-10-01)
Recent data indicate that peripheral insulin sensitivity may be influenced by dietary fat quality and skeletal muscle phospholipid fatty acid composition. During a health survey of 70-year-old men insulin sensitivity was measured by the euglycaemic hyperinsulinaemic clamp technique and the
Jonas Sieber et al.
The American journal of pathology, 183(3), 735-744 (2013-07-23)
Type 2 diabetes mellitus is characterized by dyslipidemia with elevated free fatty acids (FFAs). Loss of podocytes is a hallmark of diabetic nephropathy, and podocytes are highly susceptible to saturated FFAs but not to protective, monounsaturated FFAs. We report that
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