275514
6-Aza-2-thiothymine
99%
Synonym(s):
2-Thio-6-azathymine, 3,4-Dihydro-6-methyl-3-thioxo-1,2,4-triazin-5(2H)-one
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About This Item
Empirical Formula (Hill Notation):
C4H5N3OS
CAS Number:
Molecular Weight:
143.17
EC Number:
210-445-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
4861
MDL number:
InChI key
NKOPQOSBROLOFP-UHFFFAOYSA-N
InChI
1S/C4H5N3OS/c1-2-3(8)5-4(9)7-6-2/h1H3,(H2,5,7,8,9)
SMILES string
CC1=NNC(=S)NC1=O
assay
99%
mp
218-221 °C (lit.)
solubility
formic acid: soluble 5%, clear, colorless to light yellow-green
Application
6-Aza-2-thiothymine was used in the preparation of a matrix that was utilized for ionizing small molecules.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hao-Hua Deng et al.
Nanomaterials (Basel, Switzerland), 10(2) (2020-02-13)
This study puts forward an efficient method for protein detection in virtue of the tremendous fluorescence enhancement property of 6-aza-2-thio-thymine protected gold nanoclusters (ATT-AuNCs). In-depth studies of the protein-induced photoluminescence enhancement mechanism illustrate the mechanism of the interaction between ATT-AuNCs
Thomas Clairfeuille et al.
Nature, 584(7821), 479-483 (2020-08-14)
Lipopolysaccharide (LPS) resides in the outer membrane of Gram-negative bacteria where it is responsible for barrier function1,2. LPS can cause death as a result of septic shock, and its lipid A core is the target of polymyxin antibiotics3,4. Despite the
David Weigt et al.
Scientific reports, 8(1), 11260-11260 (2018-07-28)
Recent advances in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry have enabled whole cell-MALDI mass spectrometry biotyping of drug-treated cultured cells for rapid monitoring of known abundant pharmacodynamic protein markers such as polyacetylated histones. In contrast, generic and automated analytical workflows
Selina Rahman Shanta et al.
The Analyst, 137(24), 5757-5762 (2012-10-23)
Since the development of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, this procedure has been specifically used for analyzing proteins or high molecular weight compounds because of the interference of matrix signals in the regions of the low mass range. Recently
Shi Yan et al.
Analytical chemistry, 90(1), 928-935 (2017-11-29)
Despite years of research, the glycome of the model nematode Caenorhabditis elegans is still not fully understood. Certainly, data over the years have indicated that this organism synthesizes unusual N-glycans with a range of galactose and fucose modifications on the
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