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Merck
CN

27497

Tributyl citrate

greener alternative

≥97.0%

Synonym(s):

2-Hydroxy-1,2,3-propanetricarboxylic acid tributyl ester, Tri-n-butyl citrate

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About This Item

Empirical Formula (Hill Notation):
C18H32O7
CAS Number:
Molecular Weight:
360.44
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-071-2
Beilstein/REAXYS Number:
1806072
MDL number:
Assay:
≥97.0%
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InChI key

ZFOZVQLOBQUTQQ-UHFFFAOYSA-N

InChI

1S/C18H32O7/c1-4-7-10-23-15(19)13-18(22,17(21)25-12-9-6-3)14-16(20)24-11-8-5-2/h22H,4-14H2,1-3H3

SMILES string

CCCCOC(=O)CC(O)(CC(=O)OCCCC)C(=O)OCCCC

assay

≥97.0%

greener alternative product characteristics

Less Hazardous Chemical Syntheses
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.445

density

1.043 g/mL at 20 °C (lit.)

functional group

ester, hydroxyl

greener alternative category

Quality Level

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General description

Tributyl citrate is a common solvent and plasticizer for polymers like PVC and its copolymers that are used in food wrapping films. Also, it is a common plasticizer employed in food contact materials, cosmetics, and food additives.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product can replace highly toxic diluents in membrane preparation and thus aligns with "Less Hazardous Chemical Syntheses". Click here for more information.

Application

Tributyl citrate can be used:
  • To incorporate in zein film to enhance its mechanical properties for industrial processing.
  • As a plasticizer to improve the ductile properties of poly(lactide) polymers.

Storage Class

10 - Combustible liquids

wgk

WGK 1

ppe

Eyeshields, Gloves


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W Korsatko et al.
Die Pharmazie, 38(9), 608-611 (1983-09-01)
Matrix type tablets containing 7-hydroxyethyltheophylline, L-noradrenaline and L-isoproterenol were coated with Eudragit RS 100 film containing different concentrations of 1,2-propyleneglycol (PG) and tributylcitrate (TBC) as hydrophylic and lipophilic softeners, respectively, to effect a controlled liberation of the substances. In-vitro and
New development on plasticized poly (lactide): Chemical grafting of citrate on PLA by reactive extrusion
Hassouna F, et al.
European Polymer Journal, 48, 404-415 (2012)
Improved mechanical property and water resistance of zein films by plasticization with tributyl citrate
Shi K, et al.
Journal of Agricultural and Food Chemistry, 60, 5988-5993 (2012)
Synthesis of tributyl citrate using acid ionic liquid as catalyst
Junming XU, et al.
Process Safety and Environmental Protection, 88, 28-30 (2010)
Eva Roblegg et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(3), 635-645 (2011-08-02)
The objective of this study was the development of retarded release pellets using vegetable calcium stearate (CaSt) as a thermoplastic excipient. The matrix carrier was hot melt extruded and pelletized with a hot-strand cutter in a one step continuous process.

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