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Merck
CN

268615

3-Aminopropylphosphonic acid

98%

Synonym(s):

β-Aminopropylphosphonic acid, 3-Aminopropane-1-phosphonic acid, 3-Aminopropanephosphonic acid, 3-Azaniumylpropyl(hydroxy)phosphinate, P-(3-Aminopropyl)phosphonic acid

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About This Item

Linear Formula:
H2N(CH2)3P(O)(OH)2
CAS Number:
13138-33-5
Molecular Weight:
139.09
NACRES:
NA.22
PubChem Substance ID:
24856285
UNSPSC Code:
12352100
MDL number:
MFCD00008222
Assay:
98%
Form:
solid

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InChI

1S/C3H10NO3P/c4-2-1-3-8(5,6)7/h1-4H2,(H2,5,6,7)

SMILES string

NCCCP(O)(O)=O

InChI key

GSZQTIFGANBTNF-UHFFFAOYSA-N

assay

98%

form

solid

mp

294 °C (dec.) (lit.)

functional group

amine

Quality Level

200

Gene Information

rat ... Gabbr1(81657)

Related Categories

General description

The relative nonspecific binding of the DNA-conjugated gold nanoparticles (AuNPs) to the indium-tin oxide electrodes modified with 3-aminopropylphosphonic acid was examined by measuring the electrocatalytic anodic current of hydrazine caused by the nonspecifically absorbed AuNPs.

Application

3-Aminopropylphosphonic acid was used as a selective antagonist of GABA(C) receptor.

Biochem/physiol Actions

GABAB receptor agonist; antagonist of basal prolactin secretion.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6869V
WXBF3799V
WXBF4777V
WXBF2322V
WXBF0617V

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Replacement of ethanolamine phosphate by 3-aminopropylphosphonate in the phospholipids of Tetrahymena.
J D Smith et al.
Archives of biochemistry and biophysics, 206(2), 420-423 (1981-02-01)
C F Vaquero et al.
Neuroscience research, 35(1), 1-7 (1999-11-11)
In the vertebrate retina, the rod bipolar cells make reciprocal synapses with amacrine cells at the axon terminal. Amacrine cells may perform a fine control of the transmitter release from rod bipolar cells by means of GABAergic synapses acting on
Benny Perlstein et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 92(2), 353-360 (2009-11-12)
Nanoparticles with innovative optical, chemical, and magnetic properties combined in a single nanoparticle may be useful as biosensors, targeting agents, and therapeutic agents in the biomedical field. This study describes new magnetic nanoparticles (MNPs) containing the fluorescent dye rhodamine isothiocyanate
N V Kapousta-Bruneau
Vision research, 40(13), 1653-1665 (2000-05-18)
The largest component in the fully dark-adapted ERG is a corneal-positive response, known as the b-wave, and believed to originate from depolarizing (ON-type) bipolar cells. The two types of GABA receptors, GABA(A) and GABA(C) have been reported to exist on
Jagotamoy Das et al.
Langmuir : the ACS journal of surfaces and colloids, 25(1), 235-241 (2008-11-27)
The nonspecific binding of DNA-conjugated gold nanoparticles (AuNPs) to solid surfaces is more difficult to control than that of DNA molecules due to the more attractive interactions from the large number of DNA molecules per AuNP. This paper reports that
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