268542
Hydroxypropyl methacrylate
Mixture of hydroxypropyl and hydroxyisopropyl methacrylates, 97%, contains 180-220 ppm monomethyl ether hydroquinone as inhibitor
Synonym(s):
HPMA
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
Beilstein/REAXYS Number:
1752228
SMILES string
CC(=C)C(=O)OCCCO
InChI
1S/C7H12O3/c1-5(2)7(9)10-6(3)4-8/h6,8H,1,4H2,2-3H3
InChI key
ZMARGGQEAJXRFP-UHFFFAOYSA-N
vapor density
>1 (vs air)
vapor pressure
0.05 mmHg ( 20 °C)
assay
97%
form
liquid
contains
180-220 ppm monomethyl ether hydroquinone as inhibitor
refractive index
n20/D 1.447 (lit.)
bp
57 °C/0.5 mmHg (lit.)
density
1.066 g/mL at 25 °C (lit.)
storage temp.
2-8°C
Quality Level
Related Categories
Application
- Synthesis of poly hydroxypropyl methacrylate cryogel incorporated with Zn/Ce substituted hydroxyapatite nanoparticles for rejuvenation of femoral fracture: This study explores the synthesis of a cryogel incorporating hydroxypropyl methacrylate and Zn/Ce substituted hydroxyapatite nanoparticles, aimed at bone fracture healing (H Zhou, H Jiao, J Xu, Y Liu, S Wei, 2019).
- Poly(Hydroxypropyl methacrylate-co-glycidyl methacrylate): Facile synthesis of well-defined hydrophobic gels containing hydroxy-functional methacrylates: This article presents the synthesis of hydrophobic gels using hydroxypropyl methacrylate and glycidyl methacrylate, useful in various material applications (N Orakdogen, B Sanay, 2017).
- Initiated chemical vapor deposition of poly(Hydroxypropyl methacrylate) thin films: The study covers the chemical vapor deposition process for creating thin films of poly(hydroxypropyl methacrylate) on membranes, enhancing their functional properties (E Sevgili, M Karaman, 2019).
flash_point_f
203.0 °F - closed cup
signalword
Danger
Hazard Classifications
Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_c
95 °C - closed cup
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Annette Kelsch et al.
Biomacromolecules, 13(12), 4179-4187 (2012-11-28)
In this work we describe the application of amphiphilic N-(2-hydroxypropyl)methacrylamide (HPMA)-based copolymers as polymeric surfactants in miniemulsion techniques. HPMA-based copolymers with different ratios of HPMA (hydrophilic) to laurylmethacrylate (LMA; hydrophobic) units were synthesized by RAFT polymerization and postpolymerization modification. The
Yang Yang et al.
Biomaterials, 33(7), 2260-2271 (2011-12-23)
Galectin-3 (Gal-3), over-expressed on a variety of human tumor cells, is a potential binding site for targeted metastatic prostate cancer therapy. The aim of this study was to develop a G3-C12-mediated drug delivery system based on N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers
Adam J Gormley et al.
Journal of controlled release : official journal of the Controlled Release Society, 166(2), 130-138 (2012-12-25)
Effective drug delivery to tumors requires both transport through the vasculature and tumor interstitium. Previously, it was shown that gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) is capable of increasing the overall accumulation of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers in prostate
Stefan Hoffmann et al.
Biomacromolecules, 13(3), 652-663 (2012-01-24)
Preclinical in vivo characterization of new polymeric drug conjugate candidates is crucial for understanding the effects of certain chemical modifications on distribution and elimination of these carrier systems, which is the basis for rational drug design. In our study we
Russell N Johnson et al.
Biomacromolecules, 13(3), 727-735 (2012-02-01)
High-molecular-weight, branched N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers were synthesized and conjugated with Fab' fragments of the anti-CD20 antibody, 1F5. This produced multivalent conjugates with varying valency (amount of Fab' per macromolecule) targeted to the B-cell antigen CD20. The apoptotic activity of the
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