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268542

Sigma-Aldrich

Hydroxypropyl methacrylate

Mixture of hydroxypropyl and hydroxyisopropyl methacrylates, 97%, contains 180-220 ppm monomethyl ether hydroquinone as inhibitor

Synonym(s):

HPMA

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About This Item

CAS Number:
Beilstein:
1752228
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

>1 (vs air)

Quality Level

vapor pressure

0.05 mmHg ( 20 °C)

Assay

97%

form

liquid

contains

180-220 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.447 (lit.)

bp

57 °C/0.5 mmHg (lit.)

density

1.066 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)OCCCO

InChI

1S/C7H12O3/c1-5(2)7(9)10-6(3)4-8/h6,8H,1,4H2,2-3H3

InChI key

ZMARGGQEAJXRFP-UHFFFAOYSA-N

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Application


  • Synthesis of poly hydroxypropyl methacrylate cryogel incorporated with Zn/Ce substituted hydroxyapatite nanoparticles for rejuvenation of femoral fracture: This study explores the synthesis of a cryogel incorporating hydroxypropyl methacrylate and Zn/Ce substituted hydroxyapatite nanoparticles, aimed at bone fracture healing (H Zhou, H Jiao, J Xu, Y Liu, S Wei, 2019).

  • Poly(Hydroxypropyl methacrylate-co-glycidyl methacrylate): Facile synthesis of well-defined hydrophobic gels containing hydroxy-functional methacrylates: This article presents the synthesis of hydrophobic gels using hydroxypropyl methacrylate and glycidyl methacrylate, useful in various material applications (N Orakdogen, B Sanay, 2017).

  • Initiated chemical vapor deposition of poly(Hydroxypropyl methacrylate) thin films: The study covers the chemical vapor deposition process for creating thin films of poly(hydroxypropyl methacrylate) on membranes, enhancing their functional properties (E Sevgili, M Karaman, 2019).

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

203.0 °F - closed cup

Flash Point(C)

95 °C - closed cup


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Te-Wei Chu et al.
Biomaterials, 33(29), 7174-7181 (2012-07-17)
A hybrid biomimetic system comprising high-molecular-weight, linear copolymer of N-(2-hydroxypropyl)methacrylamide (HPMA) grafted with multiple Fab' fragments of anti-CD20 monoclonal antibody (mAb) was synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization followed by attachment of Fab' fragments via thioether bonds. Exposure
Chao Zhao et al.
Langmuir : the ACS journal of surfaces and colloids, 27(8), 4906-4913 (2011-03-17)
The development of nonfouling biomaterials to prevent nonspecific protein adsorption and cell/bacterial adhesion is critical for many biomedical applications, such as antithrombogenic implants and biosensors. In this work, we polymerize two types of hydroxy-functional methacrylates monomers of 2-hydroxyethyl methacrylate (HEMA)
Jaesung Kim et al.
Biomaterials, 33(6), 1838-1850 (2011-12-07)
With the reason that systemically administered adenovirus (Ad) is rapidly extinguished by innate/adaptive immune responses and accumulation in liver, in vivo application of the Ad vector is strictly restricted. For achieving to develop successful Ad vector systems for cancer therapy
Stefan Hoffmann et al.
Biomacromolecules, 13(3), 652-663 (2012-01-24)
Preclinical in vivo characterization of new polymeric drug conjugate candidates is crucial for understanding the effects of certain chemical modifications on distribution and elimination of these carrier systems, which is the basis for rational drug design. In our study we
Adam J Gormley et al.
Journal of controlled release : official journal of the Controlled Release Society, 166(2), 130-138 (2012-12-25)
Effective drug delivery to tumors requires both transport through the vasculature and tumor interstitium. Previously, it was shown that gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) is capable of increasing the overall accumulation of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers in prostate

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