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Safety Information

264407

Sigma-Aldrich

3,4-Difluorobenzylamine

98%

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About This Item

Linear Formula:
F2C6H3CH2NH2
CAS Number:
Molecular Weight:
143.13
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

refractive index

n20/D 1.493 (lit.)

density

1.21 g/mL at 25 °C (lit.)

functional group

amine
fluoro

SMILES string

NCc1ccc(F)c(F)c1

InChI

1S/C7H7F2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H,4,10H2

InChI key

PHLZUDXEBCQHKM-UHFFFAOYSA-N

General description

3,4-Difluorobenzylamine on condensation with glyoxal yields corresponding hexabenzyl substituted hexaazaisowurtzitanes.

Application

3,4-Difluorobenzylamine has been used in the preparation of 2-[(5-chloro-2-methoxyphenyl)sulfonyl(2-fluoroallyl)amino]-N-(3,4-difluorobenzyl)-4-pentenamide.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

174.2 °F - closed cup

Flash Point(C)

79 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Polyfluorinated hexabenzyl hexaazaisowurtzitanes.
Kerscher T, et al.
Journal of Fluorine Chemistry, 127(8), 1030-1035 (2006)
A Ring-Closing Metathesis Pathway to Fluorovinyl-Containing Nitrogen Heterocyles.
De Matteis V, et al.
European Journal of Organic Chemistry, 2006(5), 1166-1176 (2006)

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