All Photos(1)
Linear Formula:
F2C6H3NH2
CAS Number:
Molecular Weight:
129.11
Beilstein:
2802286
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
form
solid
mp
37-41 °C (lit.)
SMILES string
Nc1cc(F)cc(F)c1
InChI
1S/C6H5F2N/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2
InChI key
KQOIBXZRCYFZSO-UHFFFAOYSA-N
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General description
In vitro nephrotoxic effects of 3,5-difluoroaniline has been investigated in renal cortical slices obtained from the kidneys of untreated, male Fischer 344 rats.
Application
3,5-Difluoroaniline has been used in the preparation of 3,5-difluorodimethylaniline.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Further studies on the carcinogenicity of dyes related to 4-dimethylaminoazobenzene; the requirement for an unsubstituted 2-position.
J A MILLER et al.
Cancer research, 17(5), 387-398 (1957-06-01)
S K Hong et al.
Toxicology letters, 114(1-3), 125-133 (2000-03-14)
Haloanilines are widely used as chemical intermediates in the manufacture of pesticides, dyes and drugs. The purpose of this study was to examine the in vitro nephrotoxic effects of the four 4-haloaniline and four 3,5-dihaloaniline isomers using renal cortical slices
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