All Photos(1)
Synonym(s):
3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride, 5-Methyl-1-phenyl-1,3,4,6-tetrahydro-5H-benz[f]-2,5-oxazocine hydrochloride
Empirical Formula (Hill Notation):
C17H19NO · HCl
CAS Number:
Molecular Weight:
289.80
EC Number:
MDL number:
UNSPSC Code:
12352200
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Assay
99%
mp
260 °C (dec.) (lit.)
SMILES string
Cl.CN1CCOC(c2ccccc2)c3ccccc3C1
InChI
1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
InChI key
CNNVSINJDJNHQK-UHFFFAOYSA-N
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Biochem/physiol Actions
Nefopam is a centrally-acting analgesic drug of the benzoxazocine chemical class. Nefopam is a non-opioid, but has a potentiating effect on morphine and other opioids. Its mechanism of action is not certain, but may involve its action as a dopamine/serotonin/norepinephrine reuptake inhibitor.
Regulatory Information
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