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Merck
CN

254819

Hydroquinidine hydrochloride

98%

Synonym(s):

Dihydroquinidine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H26N2O2 · HCl
CAS Number:
Molecular Weight:
362.89
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
216-024-1
MDL number:
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InChI key

MULXTQKDWYBJMO-VJAUXQICSA-N

InChI

1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1

SMILES string

Cl.CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34

assay

98%

form

powder

optical activity

[α]20/D +185.2°, c = 1.3 in H2O

mp

277-279 °C (lit.)

functional group

hydroxyl

Quality Level

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Katsujiro Sato et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 33(8), 937-944 (2007-07-31)
Although combined use of tretinoin (all-trans-retinoic acid; atRA) and hydroquinone improves various hyperpigmented lesions, the pharmacologic instability of atRA and atRA-induced irritant dermatitis are difficult unsolved problems. The objective was to evaluate the efficacy and adverse effects of a newly
Veronica Harvey et al.
Biomedical sciences instrumentation, 38, 185-190 (2002-06-28)
Recent research in our laboratories has been directed towards the development of ionomeric polymers and monomers for use in biomedical applications such as adhesives, drug delivery matrices and tissue scaffolds. The chemical Hydroquinone (HQ) aids as a stabilizer and represents
Yuanzhi Song et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 65(2), 333-339 (2006-03-11)
Geometric parameters, the vibrational frequencies and thermochemical values of benzoquinone and hydroquinone were computed using ab initio molecular orbital calculations (HF) and density function theory (B3LYP) methods with the 6-31G(d) basis set, respectively. The calculated frequencies for benzoquinone and hydroquinone
C Kirpizidis et al.
Journal of cardiology, 38(6), 351-354 (2002-01-25)
The effectiveness of oral quinidine for conversion of atrial fibrillation to sinus rhythm was evaluated in 49 patients with persistent atrial fibrillation on anticoagulation therapy. Atrial fibrillation was considered as persistent when the duration was longer than 3 days but
Xiaoyi Wei et al.
Talanta, 77(3), 1197-1202 (2008-12-10)
An on-line solid-phase extraction (SPE)-HPLC method was developed for simultaneous screening of nicardipine and amlodipine in human plasma. A short monolithic poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) [p(GMA-EDMA)]-based weak cation-exchange (WCX) column was prepared and employed as the selective extraction sorbent, which

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