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254819

Sigma-Aldrich

Hydroquinidine hydrochloride

98%

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Synonym(s):
Dihydroquinidine hydrochloride
Empirical Formula (Hill Notation):
C20H26N2O2 · HCl
CAS Number:
1476-98-8
Molecular Weight:
362.89
EC Number:
216-024-1
MDL number:
MFCD00135598
UNSPSC Code:
12352005
PubChem Substance ID:
24855267
NACRES:
NA.22

Quality Level

100

Assay

98%

form

powder

optical activity

[α]20/D +185.2°, c = 1.3 in H2O

mp

277-279 °C (lit.)

SMILES string

Cl.CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1

InChI key

MULXTQKDWYBJMO-VJAUXQICSA-N

Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Saleem Aladaileh et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 148(4), 470-480 (2007-10-24)
Phenoloxidase (PO) activity was studied in Sydney rock oysters (Saccostrea glomerata). As in other molluscs, PO was found to exist as a pro-enzyme (proPO) in hemocytes. ProPO could be activated to PO by exogenous proteases (trypsin and chymotrypsin), exposure of
Ad Kane et al.
Annales de cardiologie et d'angeiologie, 61(4), 292-295 (2011-06-15)
A 45-year-old man was hospitalized for syncope due to fascicular ventricular tachycardia degenerating into ventricular fibrillation (VF). The electrocardiogram showed an early repolarization syndrome. The arrhythmia was repetitive and disappeared after oral hydroquinidine. An implantable cardioverter-defibrillator (ICD) was implanted; subsequently
Fiorenzo Gaita et al.
Journal of the American College of Cardiology, 43(8), 1494-1499 (2004-04-20)
The purpose of this study was to evaluate the efficacy of various antiarrhythmic drugs at prolonging the QT interval into the normal range and preventing ventricular arrhythmias in patients with short QT syndrome. Short QT syndrome is a recently described
Arti T Navare et al.
Journal of mass spectrometry : JMS, 45(6), 635-642 (2010-06-09)
Atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI) is known to suffer from poor ion transfer efficiencies as compared to conventional vacuum MALDI (vMALDI). To mitigate these issues, a new AP-MALDI ion source utilizing a coaxial gas flow was developed. Nitrogen
C K Mannesse et al.
Nederlands tijdschrift voor geneeskunde, 147(13), 585-587 (2003-04-19)
Two women, aged 77 and 73 years, and one man, aged 71 years, were admitted because of a serious adverse drug reaction (ADR). The first woman had a probable adverse drug reaction caused by digoxin after the addition of a
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