All Photos(1)
Synonym(s):
1-Naphthylamine-4-sulfonic acid, Naphthionic acid
Linear Formula:
H2NC10H6SO3H
CAS Number:
Molecular Weight:
223.25
Beilstein:
1971299
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
97%
form
powder
mp
≥300 °C (lit.)
solubility
water: very slightly soluble(lit.)
SMILES string
Nc1ccc(c2ccccc12)S(O)(=O)=O
InChI
1S/C10H9NO3S/c11-9-5-6-10(15(12,13)14)8-4-2-1-3-7(8)9/h1-6H,11H2,(H,12,13,14)
InChI key
NRZRRZAVMCAKEP-UHFFFAOYSA-N
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General description
4-Amino-1-naphthalenesulfonic acid is a diazo compound. It is also known as Piria′s acid.
Application
4-Amino-1-naphthalenesulfonic acid has potent therapeutic applications. Its sodium salt has been used as non-toxic hemostatic.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Tracing polar benzene-and naphthalenesulfonates in untreated industrial effluents and water treatment works by ion-pair chromatography-fluorescence and electrospray-mass spectrometry.
Alonso MC and Barcelo D.
Analytica Chimica Acta, 400(1), 211-231 (1999)
David E Lefebvre et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 110, 395-401 (2017-11-07)
The chemical amaranth (AM) is permitted as a colouring agent in a variety of foods. Safety was established based on chronic rodent studies. AM and its metabolite naphthionic acid (NA) can be absorbed through the intestine, exposing circulating immune cells
I Lindh et al.
Rapid communications in mass spectrometry : RCM, 8(10), 797-803 (1994-10-01)
A series of small peptides has been studied by negative-ion fast-atom bombardment mass spectrometry with collision-induced dissociation. It has been found that by derivatizing peptides with 4-aminonaphthalenesulphonic acid in a peptide linkage at the C-terminus, negative-ion formation can be enhanced
Circulating naphthionic acid in nonpregnant and pregnant rats after feeding amaranth.
R F Willes et al.
Toxicology and applied pharmacology, 54(2), 276-284 (1980-06-30)
C Juárez-Ramírez et al.
Journal of industrial microbiology & biotechnology, 39(8), 1169-1177 (2012-04-12)
By decolorization of azo dyes, caused by reductive cleavage of the azo linkage, toxic or recalcitrant amines are generated. The present study deals with the effect of the inflowing medium composition (C:N ratio) on the kinetic behavior of a bacterial
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