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Merck
CN

250619

4-Amino-1-naphthalenesulfonic acid

97%

Synonym(s):

1-Naphthylamine-4-sulfonic acid, Naphthionic acid

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About This Item

Linear Formula:
H2NC10H6SO3H
CAS Number:
84-86-6
Molecular Weight:
223.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24855065
EC Number:
201-567-9
Beilstein/REAXYS Number:
1971299
MDL number:
MFCD00004027

Key Documents

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Product Name

4-Amino-1-naphthalenesulfonic acid, 97%

InChI key

NRZRRZAVMCAKEP-UHFFFAOYSA-N

InChI

1S/C10H9NO3S/c11-9-5-6-10(15(12,13)14)8-4-2-1-3-7(8)9/h1-6H,11H2,(H,12,13,14)

SMILES string

Nc1ccc(c2ccccc12)S(O)(=O)=O

assay

97%

form

powder

mp

≥300 °C (lit.)

solubility

water: very slightly soluble(lit.)

functional group

sulfonic acid

Quality Level

200

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Application

4-Amino-1-naphthalenesulfonic acid has potent therapeutic applications. Its sodium salt has been used as non-toxic hemostatic.

General description

4-Amino-1-naphthalenesulfonic acid is a diazo compound. It is also known as Piria′s acid.

Hazard Classifications

Skin Corr. 1B

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCBM2476V
1356098V
1356098
05305HH
17725DE

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Tracing polar benzene-and naphthalenesulfonates in untreated industrial effluents and water treatment works by ion-pair chromatography-fluorescence and electrospray-mass spectrometry.
Alonso MC and Barcelo D.
Analytica Chimica Acta, 400(1), 211-231 (1999)
C Juárez-Ramírez et al.
Journal of industrial microbiology & biotechnology, 39(8), 1169-1177 (2012-04-12)
By decolorization of azo dyes, caused by reductive cleavage of the azo linkage, toxic or recalcitrant amines are generated. The present study deals with the effect of the inflowing medium composition (C:N ratio) on the kinetic behavior of a bacterial
Circulating naphthionic acid in nonpregnant and pregnant rats after feeding amaranth.
R F Willes et al.
Toxicology and applied pharmacology, 54(2), 276-284 (1980-06-30)
I Lindh et al.
Rapid communications in mass spectrometry : RCM, 8(10), 797-803 (1994-10-01)
A series of small peptides has been studied by negative-ion fast-atom bombardment mass spectrometry with collision-induced dissociation. It has been found that by derivatizing peptides with 4-aminonaphthalenesulphonic acid in a peptide linkage at the C-terminus, negative-ion formation can be enhanced
David E Lefebvre et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 110, 395-401 (2017-11-07)
The chemical amaranth (AM) is permitted as a colouring agent in a variety of foods. Safety was established based on chronic rodent studies. AM and its metabolite naphthionic acid (NA) can be absorbed through the intestine, exposing circulating immune cells
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