249580
9-Fluorenone-4-carbonyl chloride
97%
Synonym(s):
9-Oxo-4-fluorenecarbonyl chloride
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About This Item
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Assay
97%
form
solid
impurities
<2% dichloromethane
mp
139-141 °C (lit.)
storage temp.
2-8°C
SMILES string
ClC(=O)c1cccc2C(=O)c3ccccc3-c12
InChI
1S/C14H7ClO2/c15-14(17)11-7-3-6-10-12(11)8-4-1-2-5-9(8)13(10)16/h1-7H
InChI key
XKCGWCQMEUASJF-UHFFFAOYSA-N
General description
9-Fluorenone-4-carbonyl chloride is a fluorescent electrophilic reagent.
Application
9-Fluorenone-4-carbonyl chloride was used to functionalize amino acids in alkaline medium before their enantioresolution by HPLC. It was also used in the synthesis of N-(2-hydroxyethyl)-9-oxo-9H-fluorene-4 carboxamide.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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9-Fluorenon-4-carboxamides: synthesis, conformational analysis, anti-HSV-2, and immunomodulatory evaluation. Note II.
ARKIVOC (Gainesville, FL, United States), 334, 348-348 (2004)
Amino acids, 33(1), 97-104 (2006-10-28)
A fluorescent electrophilic reagent, 9-fluorenone-4-carbonyl chloride (FCC), is chosen to functionalize amino acids in alkaline medium before their HPLC resolution. FCC reacts with both primary and secondary amino acids to produce stable and highly fluorescent derivatives suitable for sensitive and
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