247847
2,6-Diaminopurine
98%
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About This Item
Empirical Formula (Hill Notation):
C5H6N6
CAS Number:
Molecular Weight:
150.14
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
217-605-2
MDL number:
InChI key
MSSXOMSJDRHRMC-UHFFFAOYSA-N
InChI
1S/C5H6N6/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H5,6,7,8,9,10,11)
SMILES string
Nc1nc(N)c2nc[nH]c2n1
assay
98%
mp
>300 °C (lit.)
Quality Level
Related Categories
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Makoto Komiyama et al.
Nature protocols, 3(4), 646-654 (2008-04-05)
Pseudo-complementary peptide nucleic acid (pcPNA) is a DNA analog in which modified DNA bases 2,6-diaminopurine (D) and 2-thiouracil (U(s)) 'decorate' a poly[N-(2-aminoethyl)glycine] backbone, together with guanine (G) and cytosine (C). One of the most significant characteristics of pcPNA is its
Anna K Shchyolkina et al.
Nucleic acids research, 34(11), 3239-3245 (2006-06-27)
Several cellular processes involve alignment of three nucleic acids strands, in which the third strand (DNA or RNA) is identical and in a parallel orientation to one of the DNA duplex strands. Earlier, using 2-aminopurine as a fluorescent reporter base
Li Qiu et al.
PLoS neglected tropical diseases, 12(4), e0006421-e0006421 (2018-04-20)
Dengue virus affects millions of people worldwide each year. To date, there is no drug for the treatment of dengue-associated disease. Nucleosides are effective antivirals and work by inhibiting the accurate replication of the viral genome. Nucleobases offer a cheaper
V Krishnakumar et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 69(1), 8-17 (2007-05-01)
FT-IR and FT-Raman spectra of 2,6-diamino purine (DAP) and 6-methoxy purine (MP) have been recorded in the regions of 4000-400cm(-1) and 3500-100cm(-1), respectively. The spectra were interpreted with the aid of normal coordinate analysis following full structure optimizations and force
André H St Amant et al.
Organic & biomolecular chemistry, 10(4), 876-881 (2011-12-14)
A Boc-protecting group strategy for Fmoc-based PNA (peptide nucleic acid) oligomerization has been developed for thymine, 2,6-diaminopurine (DAP) and 2-aminopurine (2AP). The monomers may be used interchangeably with standard Fmoc PNA monomers. The DAP monomer was incorporated into a PNA
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