247731
Hexamethylenediamine dihydrochloride
99%
Synonym(s):
1,6-Hexanediamine dihydrochloride
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About This Item
Linear Formula:
H2N(CH2)6NH2 · 2HCl
CAS Number:
Molecular Weight:
189.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
227-977-8
MDL number:
Assay:
99%
InChI key
XMVQMBLTFKAIOX-UHFFFAOYSA-N
InChI
1S/C6H16N2.2ClH/c7-5-3-1-2-4-6-8;;/h1-8H2;2*1H
SMILES string
Cl.Cl.NCCCCCCN
assay
99%
mp
256-257 °C (lit.)
solubility
water: freely soluble
functional group
amine
Quality Level
Related Categories
General description
Toxicity of hexamethylenediamine dihydrochloride has been investigated. Hexamethylenediamine dihydrochloride is also known as 1,6-diaminohexane dihydrochloride, 1,6-hexamethylenediamine dihydrochloride, 1,6- hexylenediamine dihydrochloride or 1,6-diamino-n-hexane dihydrochloride. Hexamethylenediamine dihydrochloride on fusion of 1:6-di-(N3-cyano-N1-guanidino)-hexane yields polymeric diguanides.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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850. Bisdiguanides having antibacterial activity.
Rose FL andSwain G.
Journal of the Chemical Society, 4422-4425 (1956)
Charles Hebert
Toxicity report series, 24, 1-D8-1-D8 (1993-03-01)
1,6-Hexanediamine (HDA) is an aliphatic amine that is produced in large volumes in the United States. HDA is widely used as a corrosion inhibitor in lubricants and as an intermediate in the industrial synthesis of paints, resins, inks, and textiles.
Bo Tao et al.
Polymers, 12(5) (2020-05-20)
Dopamine-modified hyaluronic acid (HA-DOP) was chosen as the drug carrier in this study, and Cu2+ was selected from among Cu2+, Zn2+, Fe2+, and Ca2+ as the central atom. 6-Mercaptopurine (6-MP) was conjugated with HA through a coordination reaction. HA-DOP-copper-MP (HA-DOP-Cu-MP)
Huina Zhang et al.
Biomaterials, 30(25), 4063-4069 (2009-06-03)
We previously established a simple method to immobilize the Arg-Gly-Asp (RGD) peptide on polycaprolactone (PCL) two-dimensional film surfaces that significantly improved bone marrow stromal cell (BMSC) adhesion to these films. The current work extends this modification strategy to three-dimensional (3D)
Linda G T Gaines et al.
The Annals of occupational hygiene, 54(6), 678-691 (2010-06-10)
Urinary 1,6-hexamethylene diamine (HDA) may serve as a biomarker for systemic exposure to 1,6-hexamethylene diisocyanate (HDI) in occupationally exposed populations. However, the quantitative relationships between dermal and inhalation exposure to HDI and urine HDA levels have not been established. We
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