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Quality Level
Assay
≥97%
form
solid
mp
184 °C (dec.) (lit.)
SMILES string
CC([O-])=O.C[N+](C)(C)C
InChI
1S/C4H12N.C2H4O2/c1-5(2,3)4;1-2(3)4/h1-4H3;1H3,(H,3,4)/q+1;/p-1
InChI key
MRYQZMHVZZSQRT-UHFFFAOYSA-M
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Cancer biotherapy & radiopharmaceuticals, 35(6), 459-473 (2020-02-06)
An α particle-emitting nanodrug that is a potent and specific antitumor agent and also prompts significant remodeling of local immunity in the tumor microenvironment (TME) has been developed and may impact the treatment of melanoma. Biocompatible ultrasmall fluorescent core-shell silica
ACS omega, 5(30), 19247-19254 (2020-08-11)
In this work, poly(ethylene terephthalate) (PET) chain-extending products with different molecular weights were prepared by reactive extrusion using isocyanate trimer (C-HK) as the trifunctional chain extender. The effect of the chain extender C-HK on the intrinsic viscosity, melt flow property
Proceedings of the National Academy of Sciences of the United States of America, 117(26), 15172-15181 (2020-06-14)
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(2), 881-891 (2018-09-27)
The impact of androgen receptor (AR) activity in breast cancer biology is unclear. We characterized and tested a novel therapy to an AR-governed target in breast cancer.Experimental Design: We evaluated the expression of prototypical AR gene products human kallikrein 2
Dalton transactions (Cambridge, England : 2003), 44(8), 3614-3623 (2014-11-20)
Chemotherapeutics for the treatment of tumorigenic conditions that feature novel modes of action are highly sought after to overcome the limitations of current chemotherapies. Herein, we report the conjugation of the alkylating agent chlorambucil to the RAPTA scaffold, a well-established
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