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Merck
CN

242497

Methyl trichloroacetate

99%

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About This Item

Linear Formula:
CCl3CO2CH3
CAS Number:
Molecular Weight:
177.41
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-960-7
Beilstein/REAXYS Number:
1756075
MDL number:
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InChI key

VHFUHRXYRYWELT-UHFFFAOYSA-N

InChI

1S/C3H3Cl3O2/c1-8-2(7)3(4,5)6/h1H3

SMILES string

COC(=O)C(Cl)(Cl)Cl

assay

99%

form

liquid

refractive index

n20/D 1.455 (lit.)

bp

152-153 °C (lit.)

density

1.488 g/mL at 25 °C (lit.)

Application

Methyl trichloroacetate was used for negative staining of protein that allowed unmodified proteins to be recovered for biological studies or transblot for amino acid sequence.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

161.6 °F - closed cup

flash_point_c

72 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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G Candiano et al.
Analytical biochemistry, 243(2), 245-248 (1996-12-15)
This paper describes a new, sensitive (in the nanogram range), and rapid (two-step) technique for the negative staining of proteins in polyacrylamide gels in the presence or absence of sodium dodecyl sulfate. After separation, gels are incubated with 8% methyl
R Bansal et al.
Arzneimittel-Forschung, 62(9), 420-424 (2012-07-14)
In this study, O-alkylated derivatives of nafimidone oxime chemically, 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime have been synthesized as potential anticonvulsant compounds. O-alkylation of the oxime using hydrochlorides of various dialkylaminoethyl chlorides, methyl chloroacetate and alkyl dihalides gave the O-alkylated derivatives. Anticonvulsant activity of
Tianlin Wang et al.
Journal of chromatography. A, 1147(1), 105-110 (2007-03-03)
This paper reports the use of methyl chloroacetate (MCA) as an extraction solvent for coupling liquid-liquid semimicroextraction (LLsME) with micellar electrokinetic chromatography (MEKC) through on-capillary decomposition for the separation of neutral compounds with concentration enhancement. Alkylphenones of C(8), C(10) and
Milena E Miska et al.
Rapid communications in mass spectrometry : RCM, 29(24), 2341-2348 (2015-11-14)
The environmental occurrence of chlorinated acetic acids (CAAs) has been extensively studied, but the sources and transport are still not yet fully understood. A promising approach for source apportionment and process studies is the isotopic characterization of target compounds. We

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