237647
L−(+)-α-Phenylglycine
99%
Synonym(s):
(S)-(+)-2-Phenylglycine, S-(+)-α-Aminophenylacetic acid, L-2-Phenylglycine
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About This Item
Linear Formula:
C6H5CH(NH2)CO2H
CAS Number:
Molecular Weight:
151.16
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-909-8
Beilstein/REAXYS Number:
2208675
MDL number:
InChI key
ZGUNAGUHMKGQNY-ZETCQYMHSA-N
InChI
1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m0/s1
SMILES string
N[C@H](C(O)=O)c1ccccc1
assay
99%
form
powder
optical activity
[α]20/D +155°, c = 1 in 1 M HCl
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
Quality Level
Application
Chiral starting material.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Henry Kurniawan et al.
Cell metabolism, 31(5), 920-936 (2020-03-28)
Regulatory T cells (Tregs) maintain immune homeostasis and prevent autoimmunity. Serine stimulates glutathione (GSH) synthesis and feeds into the one-carbon metabolic network (1CMet) essential for effector T cell (Teff) responses. However, serine's functions, linkage to GSH, and role in stress responses in
Motohiro Akazome et al.
The Journal of organic chemistry, 75(3), 660-665 (2010-01-07)
In terms of chiral recognition for racemic aryl methyl sulfoxides in the solid state, three kinds of crystalline (S)-alkylglycyl-(S)-phenylglycines were examined as potential dipeptides host molecules. When (S)-alanyl-(S)-phenylglycines [(S,S)-Ala-Phg] crystallized with aryl methyl sulfoxides, the stereochemistry of preferentially included sulfoxides
Jian-Lian Chen et al.
Analytica chimica acta, 718, 130-137 (2012-02-07)
Three different approaches for immobilizing cross-linked chitosan molecules (CS-s) in sol-gel phases to form chiral OT-CEC capillaries were comparatively investigated in this study. To synthesize column I, a bare capillary was first silanized with triethoxysilane (TEOS) and then reacted with
Aaron D Mills et al.
Bioorganic & medicinal chemistry letters, 20(1), 87-91 (2009-12-04)
A developing therapy of cystic fibrosis caused by the DeltaF508 mutation in CFTR employs correction of defective CFTR chloride channel gating by a 'potentiator' and of defective CFTR protein folding by a 'corrector'. Based on SAR data for phenylglycine-type potentiators
Hyung Min Kim et al.
The Journal of chemical physics, 128(4), 041104-041104 (2008-02-06)
Photo-oxidation of amino acids is known to generate reactive protein radicals that lead to lethal disorders. We investigated photoionization of hydrated phenylglycine complexes in the gas phase and found that the excess internal energy from photoionization drives decarboxylation in competition
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