232505
1,2-Dihydroxynaphthalene
technical grade
Synonym(s):
1,2-Naphthalenediol
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About This Item
Linear Formula:
C10H6(OH)2
CAS Number:
Molecular Weight:
160.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
209-365-2
MDL number:
InChI key
NXPPAOGUKPJVDI-UHFFFAOYSA-N
InChI
1S/C10H8O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6,11-12H
SMILES string
Oc1ccc2ccccc2c1O
grade
technical grade
mp
101-103 °C (lit.)
General description
1,2-Dihydroxynaphthalene is the most sensitive biomarker for an internal exposure to naphthalene in humans.
Application
1,2-Dihydroxynaphthalene was used as substrate to investigate the rate of oxygen consumption by washed cell suspensions of Corynebacterium sp. strain C125 grown on o-xylene, tetralin or succinate.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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E Andújar et al.
Journal of bacteriology, 182(3), 789-795 (2000-01-14)
A genomic region involved in tetralin biodegradation was recently identified in Sphingomonas strain TFA. We have cloned and sequenced from this region a gene designated thnC, which codes for an extradiol dioxygenase required for tetralin utilization. Comparison to similar sequences
Katrina L Bosward et al.
Journal of dairy science, 99(3), 2142-2150 (2016-01-19)
Streptococcus agalactiae is a well-characterized bovine mastitis pathogen that is known to be highly contagious and capable of spreading rapidly in affected dairy herds. Loop-mediated isothermal amplification (LAMP) is a novel molecular diagnostic method that has the capability to provide
Muhammad Saeed et al.
Chemico-biological interactions, 165(3), 175-188 (2007-01-17)
Naphthalene is considered by the US Environmental Protection Agency to be a carcinogenic compound based on inhalation studies in rats. The primary metabolite of naphthalene is naphthalene 1,2-arene oxide. This unstable intermediate can lead to formation of 1-naphthol and naphthalene-1,2-dihydrodiol.
Katrin Klotz et al.
International journal of hygiene and environmental health, 214(2), 110-114 (2010-12-15)
The possibly carcinogenic properties of naphthalene are, regarding to its ubiquitary presence, of environmental-medical and occupational-medical importance. Seven isomeric dihydroxynaphthalenes (DHN) were examined for their suitability as biomarkers in human biomonitoring and to get insights in human naphthalene metabolism. We
Sayamon Hongjaisee et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 102, 440-445 (2020-11-02)
The aim was to develop a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for the detection of hepatitis C virus (HCV) in a single closed tube. Plasma samples were collected from 200 HCV-infected patients. HCV-RNA was detected by one-step RT-LAMP
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