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230103

Sigma-Aldrich

2,4-Diaminophenol dihydrochloride

98%

Synonym(s):

‘Amidol’

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About This Item

Linear Formula:
(H2N)2C6H3OH·2HCl
CAS Number:
Molecular Weight:
197.06
Beilstein:
3913728
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

powder

mp

222 °C (dec.) (lit.)

SMILES string

Cl.Cl.Nc1ccc(O)c(N)c1

InChI

1S/C6H8N2O.2ClH/c7-4-1-2-6(9)5(8)3-4;;/h1-3,9H,7-8H2;2*1H

InChI key

KQEIJFWAXDQUPR-UHFFFAOYSA-N

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Application

2,4-Diaminophenol dihydrochloride (Amidol) was used in the dye manufacturing industries and as a color accelerator in photographic developers.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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National Toxicology Program technical report series, 401, 1-232 (1992-05-01)
2,4-Diaminophenol dihydrochloride is used in the manufacture of dyes and as a color accelerator in photographic developers. Toxicology and carcinogenesis studies were conducted by administering 2,4-diaminophenol dihydrochloride (greater than 97% pure) in corn oil by gavage to F344/N rats and
P N Deriabin et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (11)(11), 85-89 (1988-11-01)
Protein A has been detected in Staphylococcus aureus muriatic extracts by means of the passive hemagglutination test and the passive hemagglutination inhibition test with IgG erythrocyte diagnosticum. The absence of perceptible amounts of protein A, capable of interaction with the
[Preparation of antibody erythrocyte for indicating arbovirus antigens].
T V Kiriushchenko et al.
Voprosy virusologii, (1)(1), 98-102 (1982-01-01)
V A Shamardin
Journal of hygiene, epidemiology, microbiology, and immunology, 27(3), 265-270 (1983-01-01)
Selection of the method of loading erythrocytes with preparations of immunoglobulins (IG) should be determined by the properties of the sensitins to be used. For the production of efficient antibody diagnostics it is advisable to use amidol while in the
D G Themelis et al.
Journal of pharmaceutical and biomedical analysis, 25(5-6), 971-976 (2001-05-30)
A new simple and rapid reagent-injection method is reported for the determination of fluorides in pharmaceutical formulations. The method is based on the inhibitory effect of fluoride ions upon the Fe(III) catalytic oxidation of 2,4-diaminophenol (DAP) by H2O2. Free fluoride

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