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Merck
CN

226904

Sigma-Aldrich

Methoxyamine hydrochloride

98%

Synonym(s):

O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride

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5 G
CN¥301.37
25 G
CN¥478.72
100 G
CN¥1,937.50

CN¥301.37


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5 G
CN¥301.37
25 G
CN¥478.72
100 G
CN¥1,937.50

About This Item

Linear Formula:
CH3ONH2 · HCl
CAS Number:
Molecular Weight:
83.52
Beilstein:
3589723
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

CN¥301.37


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Quality Level

Assay

98%

form

solid

mp

151-154 °C (lit.)

solubility

alcohol: soluble(lit.)
water: soluble(lit.)

SMILES string

Cl.CON

InChI

1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H

InChI key

XNXVOSBNFZWHBV-UHFFFAOYSA-N

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1 of 4

This Item
299693638560843951
assay

98%

assay

98%

assay

97%

assay

-

density

1.259 g/mL at 25 °C (lit.)

density

1.143 g/mL at 25 °C (lit.)

density

1.148 g/mL at 25 °C (lit.)

density

1.259 g/cm3 at 25 °C

form

liquid

form

liquid

form

-

form

liquid

refractive index

n20/D 1.471 (lit.)

refractive index

n20/D 1.467 (lit.)

refractive index

n20/D 1.4470 (lit.)

refractive index

-

bp

105-107 °C/2 mmHg (lit.)

bp

166 °C/18 mmHg (lit.)

bp

76 °C/0.8 mmHg (lit.)

bp

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

General description

Methoxyamine hydrochloride combines with human antithrombin III-thrombin complex to form an inactive thrombin[1].

Application

Methoxyamine hydrochloride was used as a reagent in the preparation of O-methyl oximes[2]. It was also used in the synthesis of O-methyl oximes from aldehydes[3] or ketones[4].

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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1. Cleavage of the human antithrombin III--thrombin complex with [14C]methoxyamine hydrochloride results in inactive thrombin and 14C-labelled antithrombin III. 2. Discontinuous polyacrylamide-gel electrophoresis of the reduced dissociation fragments of the complex in the presence of sodium dodecyl sulphate reveals two
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[reaction: see text] A formal [2+2+2] process has been devised that allows the stereocontrolled formation of ring-fused piperidines from allylsilanes possessing an oxime moiety. The cascade involves an intermolecular radical addition of an alpha-iodoacetate onto an allylsilane double bond, which

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