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Merck
CN

219096

D-Aspartic acid

99%, for peptide synthesis, ReagentPlus®

Synonym(s):

(R)-(−)-Aminosuccinic acid, (R)-2-Aminosuccinic acid

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About This Item

Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
1783-96-6
Molecular Weight:
133.10
NACRES:
NA.22
PubChem Substance ID:
24853106
UNSPSC Code:
12352209
EC Number:
217-234-6
MDL number:
MFCD00063081
Beilstein/REAXYS Number:
1723529

Key Documents

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Product Name

D-Aspartic acid, ReagentPlus®, 99%

InChI key

CKLJMWTZIZZHCS-UWTATZPHSA-N

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1

SMILES string

N[C@H](CC(O)=O)C(O)=O

product line

ReagentPlus®

assay

99%

form

powder

optical activity

[α]20/D −24°, c = 2.3 in 6 M HCl

optical purity

ee: 98% (GLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (lit.)

application(s)

peptide synthesis

Quality Level

100

Gene Information

rat ... Slc1a3(29483)

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Related Categories

Application


  • Metabolomics Analysis Identifies Differential Metabolites as Biomarkers for Acute Myocardial Infarction.: This study utilizes metabolomics to identify biomarkers for acute myocardial infarction, showcasing D-Aspartic acid′s role in amino acid metabolism and potential diagnostic applications. (Zhou et al., 2024).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF5355V
WXBF2933V
WXBF0482V
WXBD6918V
WXBD4935V

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Noriko Fujii et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3141-3147 (2011-07-05)
Homochirality is essential for life. L-Amino acids are exclusively used as substrates for the polymerization and formation of peptides and proteins in living systems. However, d-amino acids, which are enantiomers of L-amino acids, were recently detected in various living organisms
H Homma
Amino acids, 32(1), 3-11 (2006-06-07)
Recent investigations have shown that D-aspartate (D-Asp) plays an important physiological role(s) in the mammalian body. Here, several recent studies of free D-Asp metabolism in mammals, focusing on cellular localization in tissues, intracellular localization, biosynthesis, efflux, uptake and degradation are
Akifumi Oda et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3337-3343 (2011-08-30)
Molecular dynamics simulations of amyloid β(1-42) containing D-aspartic acid residues were performed using several continuous solvent models to investigate the usefulness of simulation methods for D-amino acid-containing proteins and peptides. Normal molecular dynamics simulations and replica exchange molecular dynamics simulations
Francesco Errico et al.
Amino acids, 43(5), 1861-1871 (2012-08-02)
Free D-aspartate (D-Asp) occurs in substantial amounts in the brain at the embryonic phase and in the first few postnatal days, and strongly decreases in adulthood. Temporal reduction of D-Asp levels depends on the postnatal onset of D-aspartate oxidase (DDO)
Antimo D'Aniello
Brain research reviews, 53(2), 215-234 (2006-11-23)
D-Aspartic acid (d-Asp), an endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. During the embryonic stage of birds and the early postnatal
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