211281
9-Phenanthrol
technical grade
Synonym(s):
9-Hydroxyphenanthrene
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About This Item
Empirical Formula (Hill Notation):
C14H10O
CAS Number:
Molecular Weight:
194.23
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
grade
technical grade
mp
139-143 °C (lit.)
SMILES string
Oc1cc2ccccc2c3ccccc13
InChI
1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
InChI key
DZKIUEHLEXLYKM-UHFFFAOYSA-N
Application
9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes.
Biochem/physiol Actions
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Amy C Smith et al.
American journal of physiology. Cell physiology, 304(5), C467-C477 (2013-01-11)
Members of the transient receptor potential (TRP) channel superfamily, including the Ca(2+)-activated monovalent cation-selective TRP melastatin 4 (TRPM4) channel, have been recently identified in the urinary bladder. However, their expression and function at the level of detrusor smooth muscle (DSM)
Stefano Masoli et al.
Communications biology, 3(1), 222-222 (2020-05-10)
The cerebellar granule cells (GrCs) are classically described as a homogeneous neuronal population discharging regularly without adaptation. We show that GrCs in fact generate diverse response patterns to current injection and synaptic activation, ranging from adaptation to acceleration of firing.
Te-Ling Lu et al.
Biomolecules, 10(2) (2020-01-30)
: GAL-021 has recently been developed as a novel breathing control modulator. However, modifications of ionic currents produced by this agent remain uncertain, although its efficacy in suppressing the activity of big-conductance Ca2+-activated K+ (BKCa) channels has been reported. In
J Lintelmann et al.
Journal of chromatography. B, Biomedical applications, 660(1), 67-73 (1994-10-03)
A coupled-column high-performance liquid chromatographic method applying system-integrated sample processing on a copper phthalocyanine modified solid-phase material, gradient elution and fluorescence detection for the quantification of 1-, 4- and 9-hydroxyphenanthrene as well as for 1-hydroxypyrene in urine is described. The
R Guinamard et al.
British journal of pharmacology, 171(7), 1600-1613 (2014-01-18)
The phenanthrene-derivative 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whose mechanism of action remains to be determined. Subsequent studies performed on other ion channels confirm the
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