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207713

Sigma-Aldrich

1,3-Di-o-tolylguanidine

99%

Synonym(s):

DTG

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About This Item

Linear Formula:
(CH3C6H4NH)2C(=NH)
CAS Number:
97-39-2
Molecular Weight:
239.32
EC Number:
202-577-6
MDL number:
MFCD00008513
UNSPSC Code:
12352100
PubChem Substance ID:
24852467
NACRES:
NA.22

Quality Level

100

Assay

99%

form

solid

mp

176-178 °C (lit.)

solubility

water: soluble 70 mg/mL at 20 °C

functional group

amine

SMILES string

Cc1ccccc1NC(=N)Nc2ccccc2C

InChI

1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)

InChI key

OPNUROKCUBTKLF-UHFFFAOYSA-N

Gene Information

human ... EBP(10682)

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General description

1,3-Di-o-tolylguanidine is a selective σ-receptor agonist. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW7506
MKCV7802
MKCW1599
MKCW1600
MKCW8211

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    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

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    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

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  5. What is the solubility of Product 207713, 1,3-di-o-tolylguanidine?

    1,3-Di-o-tolylguanidine is soluble in water at 70 micrograms per mL at ambient temperature.

  6. What is the nature of the biological activity of Product 207713, 1,3-di-o-tolylguanidine?

    1,3-Di-o-tolylguanidine is known to be a selective ligand for the sigma site in the mammalian central nervous system. Behavioral changes, such as hypothermia, reduced pain behavior, circling behavior, and decreased locomotor activity in mice and/or rats were observed after intraperitoneal, subcutaneous, intravenous and/or intranigral injection.

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