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Merck
CN

202789

Beryllium sulfate tetrahydrate

99.99% trace metals basis

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About This Item

Linear Formula:
BeSO4 · 4H2O
CAS Number:
7787-56-6
Molecular Weight:
177.14
NACRES:
NA.22
PubChem Substance ID:
24852118
UNSPSC Code:
12352302
EC Number:
236-842-2
MDL number:
MFCD00149156

Key Documents

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InChI key

DIMYTQPLZWDZFE-UHFFFAOYSA-L

InChI

1S/Be.H2O4S.4H2O/c;1-5(2,3)4;;;;/h;(H2,1,2,3,4);4*1H2/q+2;;;;;/p-2

SMILES string

[Be++].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[O-]S([O-])(=O)=O

assay

99.99% trace metals basis

density

1.713 g/mL at 25 °C (lit.)

Application

Used in study of the dicarboxylate chelation of beryllium in an attempt to understand its physiological chemistry.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation - STOT SE 3

target_organs

Respiratory system, Skin,Respiratory Tract

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCH6025
MKCG4241
MKCC1678
MKBP5108V
MKAA3609

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Michael Schmidt et al.
Inorganic chemistry, 36(10), 2040-2043 (1997-05-07)
Maleic and phthalic acids are found to react with Be(OH)(2), generated in situ from BeSO(4)(aq) and Ba(OH)(2)(aq), in aqueous solution at pH 3.0 or 4.4, respectively (25 degrees C), to give solutions containing the complexes (H(2)O)(2)Be[(OOCCH)(2)] (1) and (H(2)O)(2)Be[(OOC)(2)C(6)H(4)] (3).
Priyatham Gorjala et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 23(6), 1061-1073 (2010-06-16)
In fibroblasts, beryllium salt causes activation of the p53 transcription factor and induction of a senescence-like state. It is not known whether Be(2+) can affect the proliferation of cancer cells, which are generally unsusceptible to senescence. A172 glioblastoma and RKO
Chronic beryllium disease: T cell recognition of a metal presented by HLA-DP.
A P Fontenot et al.
Clinical immunology (Orlando, Fla.), 100(1), 4-14 (2001-06-21)
Richard T Sawyer et al.
Free radical biology & medicine, 38(7), 928-937 (2005-03-08)
Beryllium (Be), the etiologic agent of chronic beryllium disease, is a toxic metal that induces apoptosis in human alveolar macrophages. We tested the hypothesis that Be stimulates the formation of reactive oxygen species (ROS) which plays a role in Be-induced
Andrew P Fontenot et al.
The Journal of clinical investigation, 110(10), 1473-1482 (2002-11-20)
Chronic beryllium disease (CBD) is caused by exposure to beryllium in the workplace, and it remains an important public health concern. Evidence suggests that CD4(+) T cells play a critical role in the development of this disease. Using intracellular cytokine
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